Vertically aligned carbon nanofiber neural chip for interfacing with neurological system

Zhe Yu, Timothy E. McKnight, M. Nance Ericson, Anatoli V. Melechko, Michael L. Simpson, Barclay Morrison

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

Neual chips have been used to detect and modulate neuroelectrical activity for almost 30 years. Their capability of simultaneous, multi-site recording enable neuroscientists to study neural signal processing through neural circuits. By improving sensitivity and spatial resolution, nano scale neural chips may revolutionize neural detection and modulation at cellular and molecular levels. We developed a carbon-nanofiber neural chip with lithographically defined arrays of vertically aligned carbon nanofiber electrodes and demonstrated its capability of both stimulating and monitoring electrophysiological signals from brain tissues in vitro. This novel neural chip can potentially serve as dual-mode neural interface for monitoring of both neuroelectrical and neurochemical activity by simultaneous recording of electrophysiology and neurotransmitter concentration.

Original languageEnglish
Title of host publication2010 IEEE International Conference on Nano/Molecular Medicine and Engineering, IEEE NANOMED 2010
Pages188-191
Number of pages4
DOIs
StatePublished - 2010
Event4th IEEE International Conference on Nano/Molecular Medicine and Engineering, IEEE NANOMED 2010 - Hong Kong/Macau, China
Duration: Dec 5 2010Dec 9 2010

Publication series

Name2010 IEEE International Conference on Nano/Molecular Medicine and Engineering, IEEE NANOMED 2010

Conference

Conference4th IEEE International Conference on Nano/Molecular Medicine and Engineering, IEEE NANOMED 2010
Country/TerritoryChina
CityHong Kong/Macau
Period12/5/1012/9/10

Keywords

  • Carbon nanofiber
  • electrophysiology
  • microelectrode array
  • neural chip
  • neural interface

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