Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology

R. E. Morris; K. E. Albanese; M. N. Lakshmanan; S. J. McCall; J. A. Greenberg; A. J. Kapadia

doi:10.1117/12.2216974

Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology

R. E. Morris, K. E. Albanese, M. N. Lakshmanan, S. J. McCall, J. A. Greenberg, A. J. Kapadia

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

4 Scopus citations

Abstract

This study intends to validate the sensitivity and specificity of coded aperture coherent scatter spectral imaging (CACSSI) by comparison to standard histological preparation and pathologic analysis methods used to differentiate normal and neoplastic breast tissues. A composite overlay of the CACSSI rendered image and pathologist interpreted stained sections validate the ability of CACSSI to differentiate normal and neoplastic breast structures ex-vivo. Via comparison to pathologist annotated slides, the CACSSI system may be further optimized to maximize sensitivity and specificity for differentiation of breast carcinomas.

Original language	English
Title of host publication	Medical Imaging 2016
Subtitle of host publication	Physics of Medical Imaging
Editors	Despina Kontos, Joseph Y. Lo, Thomas G. Flohr
Publisher	SPIE
ISBN (Electronic)	9781510600188
DOIs	https://doi.org/10.1117/12.2216974
State	Published - 2016
Externally published	Yes
Event	Medical Imaging 2016: Physics of Medical Imaging - San Diego, United States Duration: Feb 28 2016 → Mar 2 2016

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9783
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2016: Physics of Medical Imaging
Country/Territory	United States
City	San Diego
Period	02/28/16 → 03/2/16

Keywords

breast carcinoma
breast imaging
spectral imaging
x-ray coherent scatter

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1117/12.2216974

Cite this

Morris, R. E., Albanese, K. E., Lakshmanan, M. N., McCall, S. J., Greenberg, J. A., & Kapadia, A. J. (2016). Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology. In D. Kontos, J. Y. Lo, & T. G. Flohr (Eds.), Medical Imaging 2016: Physics of Medical Imaging Article 97835T (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9783). SPIE. https://doi.org/10.1117/12.2216974

Morris, R. E. ; Albanese, K. E. ; Lakshmanan, M. N. et al. / Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology. Medical Imaging 2016: Physics of Medical Imaging. editor / Despina Kontos ; Joseph Y. Lo ; Thomas G. Flohr. SPIE, 2016. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

@inproceedings{6f4b26870d99421485838f56df15e70b,

title = "Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology",

abstract = "This study intends to validate the sensitivity and specificity of coded aperture coherent scatter spectral imaging (CACSSI) by comparison to standard histological preparation and pathologic analysis methods used to differentiate normal and neoplastic breast tissues. A composite overlay of the CACSSI rendered image and pathologist interpreted stained sections validate the ability of CACSSI to differentiate normal and neoplastic breast structures ex-vivo. Via comparison to pathologist annotated slides, the CACSSI system may be further optimized to maximize sensitivity and specificity for differentiation of breast carcinomas.",

keywords = "breast carcinoma, breast imaging, spectral imaging, x-ray coherent scatter",

author = "Morris, {R. E.} and Albanese, {K. E.} and Lakshmanan, {M. N.} and McCall, {S. J.} and Greenberg, {J. A.} and Kapadia, {A. J.}",

note = "Publisher Copyright: {\textcopyright} 2016 SPIE.; Medical Imaging 2016: Physics of Medical Imaging ; Conference date: 28-02-2016 Through 02-03-2016",

year = "2016",

doi = "10.1117/12.2216974",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Despina Kontos and Lo, {Joseph Y.} and Flohr, {Thomas G.}",

booktitle = "Medical Imaging 2016",

}

Morris, RE, Albanese, KE, Lakshmanan, MN, McCall, SJ, Greenberg, JA & Kapadia, AJ 2016, Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology. in D Kontos, JY Lo & TG Flohr (eds), Medical Imaging 2016: Physics of Medical Imaging., 97835T, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9783, SPIE, Medical Imaging 2016: Physics of Medical Imaging, San Diego, United States, 02/28/16. https://doi.org/10.1117/12.2216974

Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology. / Morris, R. E.; Albanese, K. E.; Lakshmanan, M. N. et al.
Medical Imaging 2016: Physics of Medical Imaging. ed. / Despina Kontos; Joseph Y. Lo; Thomas G. Flohr. SPIE, 2016. 97835T (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9783).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology

AU - Morris, R. E.

AU - Albanese, K. E.

AU - Lakshmanan, M. N.

AU - McCall, S. J.

AU - Greenberg, J. A.

AU - Kapadia, A. J.

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Y1 - 2016

N2 - This study intends to validate the sensitivity and specificity of coded aperture coherent scatter spectral imaging (CACSSI) by comparison to standard histological preparation and pathologic analysis methods used to differentiate normal and neoplastic breast tissues. A composite overlay of the CACSSI rendered image and pathologist interpreted stained sections validate the ability of CACSSI to differentiate normal and neoplastic breast structures ex-vivo. Via comparison to pathologist annotated slides, the CACSSI system may be further optimized to maximize sensitivity and specificity for differentiation of breast carcinomas.

AB - This study intends to validate the sensitivity and specificity of coded aperture coherent scatter spectral imaging (CACSSI) by comparison to standard histological preparation and pathologic analysis methods used to differentiate normal and neoplastic breast tissues. A composite overlay of the CACSSI rendered image and pathologist interpreted stained sections validate the ability of CACSSI to differentiate normal and neoplastic breast structures ex-vivo. Via comparison to pathologist annotated slides, the CACSSI system may be further optimized to maximize sensitivity and specificity for differentiation of breast carcinomas.

KW - breast carcinoma

KW - breast imaging

KW - spectral imaging

KW - x-ray coherent scatter

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DO - 10.1117/12.2216974

M3 - Conference contribution

AN - SCOPUS:84978910295

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2016

A2 - Kontos, Despina

A2 - Lo, Joseph Y.

A2 - Flohr, Thomas G.

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ER -

Morris RE, Albanese KE, Lakshmanan MN, McCall SJ, Greenberg JA, Kapadia AJ. Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology. In Kontos D, Lo JY, Flohr TG, editors, Medical Imaging 2016: Physics of Medical Imaging. SPIE. 2016. 97835T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2216974

Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology

Abstract

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Keywords

UN SDGs

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