Two-component membrane lithography via lipid backfilling

Seung Yong Jung, Matthew A. Holden, Paul S. Cremer, C. Patrick Collier

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

A novel lithographic technique to pattern artificial lipid bilayer microdomains has been developed which exploits the limited mobility of gel-phase phospholipids. With this technique, fluid microdomains could be patterned into a solid gel-like matrix or gel-like lipids could be patterned in a sea of fluid lipids. In both cases, the patterned areas form a cohesive and contiguous supported lipid bilayer membrane (see picture).

Original languageEnglish
Pages (from-to)423-426
Number of pages4
JournalChemPhysChem
Volume6
Issue number3
DOIs
StatePublished - Mar 2005
Externally publishedYes

Keywords

  • Lipids
  • Membranes
  • Microcontact printing
  • Phase segregation
  • Polydimethylsiloxane

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