ToFFi – Toolbox for frequency-based fingerprinting of brain signals

Michał K. Komorowski, Krzysztof Rykaczewski, Tomasz Piotrowski, Katarzyna Jurewicz, Jakub Wojciechowski, Anne Keitel, Joanna Dreszer, Włodzisław Duch

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Spectral fingerprints (SFs) are unique power spectra signatures of human brain regions of interest (ROIs, Keitel & Gross, 2016). SFs allow for accurate ROI identification and can serve as biomarkers of differences exhibited by non-neurotypical groups. At present, there are no open-source, versatile tools to calculate spectral fingerprints. We have filled this gap by creating a modular, highly-configurable MATLAB Toolbox for Frequency-based Fingerprinting (ToFFi). It can transform magnetoencephalographic and electroencephalographic signals into unique spectral representations using ROIs provided by anatomical (AAL, Desikan-Killiany), functional (Schaefer), or other custom volumetric brain parcellations. Toolbox design supports reproducibility and parallel computations.

Original languageEnglish
Article number126236
JournalNeurocomputing
Volume544
DOIs
StatePublished - Aug 1 2023
Externally publishedYes

Funding

Funding: This work has been supported by the National Science Centre, Poland, grant UMO-2016/20/W/NZ4/00354. Data were provided [in part] by the Human Connectome Project, WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University. Calculations were carried out at the Tricity Academic Supercomputer & Network Center in Gdańsk. We thank professor Joachim Gross for his generous technical support, Ewa Ratajczak, and Bartosz Kochański for helping out with testing and debugging the software.

Keywords

  • Biomarkers
  • Brain fingerprinting
  • Computational neuroscience
  • Source localization
  • Spectral fingerprints

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