The radiochemical and radiopharmaceutical applications of radium

Matthew Gott, Jörg Steinbach, Constantin Mamat

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations

Abstract

This review focuses on the chemistry and application of radium isotopes to environmental monitoring, analytical, and medicinal uses. In recent years, radium has been used primarily as a tracer to study the migration of radioactive substances in environmental systems. Tracing the naturally occurring radium isotopes in mineral and water sources allows for the determination of source location, residence time, and concentrations. An understanding of the concentration of radionuclides in our food and water sources is essential to everyone's health as alpha particle decay is highly damaging in vivo. Due to this high radiobiological effectiveness, there is increased interest in using alpha-emitting radionuclides to prepare new, therapeutic radiopharmaceutical drugs. Selected studies from the recent literature are provided as examples of these modern applications of radium isotopes.

Original languageEnglish
Pages (from-to)118-129
Number of pages12
JournalOpen Chemistry
Volume14
Issue number1
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

Keywords

  • Alpha emitters
  • Radiochronology
  • Radiotherapy
  • Radiotracers
  • Radium

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