Abstract
Facile reactivity of hydrazides and aldehydes was explored as potential coupling partners for incorporation into M(CO)3 (M = Re, 99mTc) based radiopharmaceuticals. Both 'click, then chelate' and 'prelabel, then click' synthetic routes produced identical products in high yields and lacked metal-hydrazide/-hydrazone interactions, highlighting the potential of this click strategy.
Original language | English |
---|---|
Pages (from-to) | 12846-12848 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 47 |
Issue number | 48 |
DOIs | |
State | Published - Dec 28 2011 |
Externally published | Yes |