The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

Hans Peter Klenk; Rebecca A. Clayton; Jean Francois Tomb; Owen White; Karen E. Nelson; Karen A. Ketchum; Robert J. Dodson; Michelle Gwinn; Erin K. Hickey; Jeremy D. Peterson; Delwood L. Richardson; Anthony R. Kerlavage; David E. Graham; Nikos C. Krypides; Robert D. Fleischmann; John Quackenbush; Norman H. Lee; Granger G. Sutton; Steven Gill; Ewen F. Kirkness; Brian A. Dougherty; Keith McKenney; Mark D. Adams; Brendan Loftus; Scott Peterson; Claudia I. Reich; Leslie K. McNeil; Jonathan H. Badger; Anna Glodek; Lixin Zhou; Ross Overbeek; Jeannine D. Gocayne; Janice F. Wiedman; Lisa McDonald; Teresa Utterback; Matthew D. Cotton; Tracy Spriggs; Patricia Artiach; Brian P. Kaine; Sean M. Sykes; Paul W. Sadow; Kurt P. D'Andrea; Cheryl Bowman; Claire Fujii; Stacey A. Garland; Tanya M. Mason; Gary J. Olsen; Claire M. Fraser; Hamilton O. Smith; Carl R. Woese; J. Craig Venter

doi:10.1038/37052

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

Hans Peter Klenk, Rebecca A. Clayton, Jean Francois Tomb, Owen White, Karen E. Nelson, Karen A. Ketchum, Robert J. Dodson, Michelle Gwinn, Erin K. Hickey, Jeremy D. Peterson, Delwood L. Richardson, Anthony R. Kerlavage, David E. Graham, Nikos C. Krypides, Robert D. Fleischmann, John Quackenbush, Norman H. Lee, Granger G. Sutton, Steven Gill, Ewen F. KirknessBrian A. Dougherty, Keith McKenney, Mark D. Adams, Brendan Loftus, Scott Peterson, Claudia I. Reich, Leslie K. McNeil, Jonathan H. Badger, Anna Glodek, Lixin Zhou, Ross Overbeek, Jeannine D. Gocayne, Janice F. Wiedman, Lisa McDonald, Teresa Utterback, Matthew D. Cotton, Tracy Spriggs, Patricia Artiach, Brian P. Kaine, Sean M. Sykes, Paul W. Sadow, Kurt P. D'Andrea, Cheryl Bowman, Claire Fujii, Stacey A. Garland, Tanya M. Mason, Gary J. Olsen, Claire M. Fraser, Hamilton O. Smith, Carl R. Woese, J. Craig Venter

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Abstract

Archaeoglobus fulgidus is the first sulphur-metabolizing organism to have its genome sequence determined. Its genome of 2,178,400 base pairs contains 2,436 open reading frames (ORFs). The information processing systems and the biosynthetic pathways for essential components (nucleotides, amino acids and cofactors) have extensive correlation with their counterparts in the archaeon Methanococcus jannaschii. The genomes of these two Archaea indicate dramatic differences in the way these organisms sense their environment, perform regulatory and transport functions, and gain energy. In contrast to M. jannaschii, A. fulgidus has fewer restriction-modification systems, and none of its genes appears to contain inteins. A quarter (651 ORFs) of the A. fulgidus genome encodes functionally uncharacterized yet conserved proteins, two-thirds of which are shared with M. jannaschii (428 ORFs). Another quarter of the genome encodes new proteins indicating substantial archaeal gene diversity.

Original language	English
Pages (from-to)	364-370
Number of pages	7
Journal	Nature
Volume	390
Issue number	6658
DOIs	https://doi.org/10.1038/37052
State	Published - Nov 27 1997
Externally published	Yes

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Klenk, H. P., Clayton, R. A., Tomb, J. F., White, O., Nelson, K. E., Ketchum, K. A., Dodson, R. J., Gwinn, M., Hickey, E. K., Peterson, J. D., Richardson, D. L., Kerlavage, A. R., Graham, D. E., Krypides, N. C., Fleischmann, R. D., Quackenbush, J., Lee, N. H., Sutton, G. G., Gill, S., ... Craig Venter, J. (1997). The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus. Nature, 390(6658), 364-370. https://doi.org/10.1038/37052

@article{80232ca64a7246af8ce4d5cd5354793d,

title = "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus",

abstract = "Archaeoglobus fulgidus is the first sulphur-metabolizing organism to have its genome sequence determined. Its genome of 2,178,400 base pairs contains 2,436 open reading frames (ORFs). The information processing systems and the biosynthetic pathways for essential components (nucleotides, amino acids and cofactors) have extensive correlation with their counterparts in the archaeon Methanococcus jannaschii. The genomes of these two Archaea indicate dramatic differences in the way these organisms sense their environment, perform regulatory and transport functions, and gain energy. In contrast to M. jannaschii, A. fulgidus has fewer restriction-modification systems, and none of its genes appears to contain inteins. A quarter (651 ORFs) of the A. fulgidus genome encodes functionally uncharacterized yet conserved proteins, two-thirds of which are shared with M. jannaschii (428 ORFs). Another quarter of the genome encodes new proteins indicating substantial archaeal gene diversity.",

author = "Klenk, {Hans Peter} and Clayton, {Rebecca A.} and Tomb, {Jean Francois} and Owen White and Nelson, {Karen E.} and Ketchum, {Karen A.} and Dodson, {Robert J.} and Michelle Gwinn and Hickey, {Erin K.} and Peterson, {Jeremy D.} and Richardson, {Delwood L.} and Kerlavage, {Anthony R.} and Graham, {David E.} and Krypides, {Nikos C.} and Fleischmann, {Robert D.} and John Quackenbush and Lee, {Norman H.} and Sutton, {Granger G.} and Steven Gill and Kirkness, {Ewen F.} and Dougherty, {Brian A.} and Keith McKenney and Adams, {Mark D.} and Brendan Loftus and Scott Peterson and Reich, {Claudia I.} and McNeil, {Leslie K.} and Badger, {Jonathan H.} and Anna Glodek and Lixin Zhou and Ross Overbeek and Gocayne, {Jeannine D.} and Wiedman, {Janice F.} and Lisa McDonald and Teresa Utterback and Cotton, {Matthew D.} and Tracy Spriggs and Patricia Artiach and Kaine, {Brian P.} and Sykes, {Sean M.} and Sadow, {Paul W.} and D'Andrea, {Kurt P.} and Cheryl Bowman and Claire Fujii and Garland, {Stacey A.} and Mason, {Tanya M.} and Olsen, {Gary J.} and Fraser, {Claire M.} and Smith, {Hamilton O.} and Woese, {Carl R.} and {Craig Venter}, J.",

year = "1997",

month = nov,

day = "27",

doi = "10.1038/37052",

language = "English",

volume = "390",

pages = "364--370",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Research",

number = "6658",

}

Klenk, HP, Clayton, RA, Tomb, JF, White, O, Nelson, KE, Ketchum, KA, Dodson, RJ, Gwinn, M, Hickey, EK, Peterson, JD, Richardson, DL, Kerlavage, AR, Graham, DE, Krypides, NC, Fleischmann, RD, Quackenbush, J, Lee, NH, Sutton, GG, Gill, S, Kirkness, EF, Dougherty, BA, McKenney, K, Adams, MD, Loftus, B, Peterson, S, Reich, CI, McNeil, LK, Badger, JH, Glodek, A, Zhou, L, Overbeek, R, Gocayne, JD, Wiedman, JF, McDonald, L, Utterback, T, Cotton, MD, Spriggs, T, Artiach, P, Kaine, BP, Sykes, SM, Sadow, PW, D'Andrea, KP, Bowman, C, Fujii, C, Garland, SA, Mason, TM, Olsen, GJ, Fraser, CM, Smith, HO, Woese, CR & Craig Venter, J 1997, 'The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus', Nature, vol. 390, no. 6658, pp. 364-370. https://doi.org/10.1038/37052

TY - JOUR

T1 - The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

AU - Klenk, Hans Peter

AU - Clayton, Rebecca A.

AU - Tomb, Jean Francois

AU - White, Owen

AU - Nelson, Karen E.

AU - Ketchum, Karen A.

AU - Dodson, Robert J.

AU - Gwinn, Michelle

AU - Hickey, Erin K.

AU - Peterson, Jeremy D.

AU - Richardson, Delwood L.

AU - Kerlavage, Anthony R.

AU - Graham, David E.

AU - Krypides, Nikos C.

AU - Fleischmann, Robert D.

AU - Quackenbush, John

AU - Lee, Norman H.

AU - Sutton, Granger G.

AU - Gill, Steven

AU - Kirkness, Ewen F.

AU - Dougherty, Brian A.

AU - McKenney, Keith

AU - Adams, Mark D.

AU - Loftus, Brendan

AU - Peterson, Scott

AU - Reich, Claudia I.

AU - McNeil, Leslie K.

AU - Badger, Jonathan H.

AU - Glodek, Anna

AU - Zhou, Lixin

AU - Overbeek, Ross

AU - Gocayne, Jeannine D.

AU - Wiedman, Janice F.

AU - McDonald, Lisa

AU - Utterback, Teresa

AU - Cotton, Matthew D.

AU - Spriggs, Tracy

AU - Artiach, Patricia

AU - Kaine, Brian P.

AU - Sykes, Sean M.

AU - Sadow, Paul W.

AU - D'Andrea, Kurt P.

AU - Bowman, Cheryl

AU - Fujii, Claire

AU - Garland, Stacey A.

AU - Mason, Tanya M.

AU - Olsen, Gary J.

AU - Fraser, Claire M.

AU - Smith, Hamilton O.

AU - Woese, Carl R.

AU - Craig Venter, J.

PY - 1997/11/27

Y1 - 1997/11/27

N2 - Archaeoglobus fulgidus is the first sulphur-metabolizing organism to have its genome sequence determined. Its genome of 2,178,400 base pairs contains 2,436 open reading frames (ORFs). The information processing systems and the biosynthetic pathways for essential components (nucleotides, amino acids and cofactors) have extensive correlation with their counterparts in the archaeon Methanococcus jannaschii. The genomes of these two Archaea indicate dramatic differences in the way these organisms sense their environment, perform regulatory and transport functions, and gain energy. In contrast to M. jannaschii, A. fulgidus has fewer restriction-modification systems, and none of its genes appears to contain inteins. A quarter (651 ORFs) of the A. fulgidus genome encodes functionally uncharacterized yet conserved proteins, two-thirds of which are shared with M. jannaschii (428 ORFs). Another quarter of the genome encodes new proteins indicating substantial archaeal gene diversity.

AB - Archaeoglobus fulgidus is the first sulphur-metabolizing organism to have its genome sequence determined. Its genome of 2,178,400 base pairs contains 2,436 open reading frames (ORFs). The information processing systems and the biosynthetic pathways for essential components (nucleotides, amino acids and cofactors) have extensive correlation with their counterparts in the archaeon Methanococcus jannaschii. The genomes of these two Archaea indicate dramatic differences in the way these organisms sense their environment, perform regulatory and transport functions, and gain energy. In contrast to M. jannaschii, A. fulgidus has fewer restriction-modification systems, and none of its genes appears to contain inteins. A quarter (651 ORFs) of the A. fulgidus genome encodes functionally uncharacterized yet conserved proteins, two-thirds of which are shared with M. jannaschii (428 ORFs). Another quarter of the genome encodes new proteins indicating substantial archaeal gene diversity.

UR - http://www.scopus.com/inward/record.url?scp=0031458333&partnerID=8YFLogxK

U2 - 10.1038/37052

DO - 10.1038/37052

M3 - Article

C2 - 9389475

AN - SCOPUS:0031458333

SN - 0028-0836

VL - 390

SP - 364

EP - 370

JO - Nature

JF - Nature

IS - 6658

ER -

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

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