The Aggregation behavior of DNA-conjugated gold nanoparticles

Shizuto Yamakoshi, Yasuhiro Sakai, Kohzo Ito, Yuuya Shinohara, Yoshiyuki Amemiya, Naoki Kanayama, Tohru Takarada, Mizuo Maeda

Research output: Contribution to conferencePaperpeer-review

Abstract

DNA-conjugated gold nanoparticles exhibit a unique aggregation behavior that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form.This suggests that the ends of completely double-strand DNA conjugated on gold nanoparticles contact or interdigitate slightly with each other in the aggeregation structure.

Original languageEnglish
Pages4833
Number of pages1
StatePublished - 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Conference

Conference55th Society of Polymer Science Japan Symposium on Macromolecules
Country/TerritoryJapan
CityToyama
Period09/20/0609/22/06

Keywords

  • Aggregate
  • Colloid
  • DNA
  • Gold nanoparticle
  • SAXS
  • SNPs

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