The A, C, G, and T of genome assembly

Bilal Wajid; Muhammad U. Sohail; Ali R. Ekti; Erchin Serpedin

doi:10.1155/2016/6329217

The A, C, G, and T of genome assembly

Bilal Wajid
, Muhammad U. Sohail
, Ali R. Ekti
, Erchin Serpedin

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.

Original language	English
Article number	6329217
Journal	BioMed Research International
Volume	2016
DOIs	https://doi.org/10.1155/2016/6329217
State	Published - 2016
Externally published	Yes

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title = "The A, C, G, and T of genome assembly",

abstract = "Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.",

author = "Bilal Wajid and Sohail, \{Muhammad U.\} and Ekti, \{Ali R.\} and Erchin Serpedin",

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AU - Wajid, Bilal

AU - Sohail, Muhammad U.

AU - Ekti, Ali R.

AU - Serpedin, Erchin

PY - 2016

Y1 - 2016

N2 - Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.

AB - Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.

UR - https://www.scopus.com/pages/publications/84973300728

U2 - 10.1155/2016/6329217

DO - 10.1155/2016/6329217

M3 - Review article

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AN - SCOPUS:84973300728

SN - 2314-6133

VL - 2016

JO - BioMed Research International

JF - BioMed Research International

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The A, C, G, and T of genome assembly

Abstract

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