TBu₃P-coordinated 2-phenylaniline-based palladacycle complexes as precatalyst for Pd-catalyzed coupling reactions of aryl halides with polyfluoroarenes by a C-H activation strategy

A tBu₃P-coordinated 2-phenylaniline-based palladacycle complex was demonstrated to be an efficient precatalyst for Pd-catalyzed coupling reactions of aryl halides with polyfluoroarenes that operates through a C-H activation strategy. The ready accessibility and ease of handling of the complex and the high yields of the reaction makes this palladacycle complex an attractive precatalyst for the cross-coupling reaction of aryl halides with polyfluoroarenes. A tBu₃P-coordinated 2-phenylaniline-based palladacycle complex was found to be an efficient precatalyst for Pd-catalyzed coupling reactions of aryl halides with polyfluoroarenes that operates through a C-H activation strategy, with good to excellent product yields being observed.