Synthetic Biology and Metabolic Engineering Employing Escherichia coli for C2–C6 Bioalcohol Production

Liya Liang; Rongming Liu; Emily F. Freed; Carrie A. Eckert

doi:10.3389/fbioe.2020.00710

Synthetic Biology and Metabolic Engineering Employing Escherichia coli for C2–C6 Bioalcohol Production

Liya Liang, Rongming Liu, Emily F. Freed, Carrie A. Eckert

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

Abstract

Biofuel production from renewable and sustainable resources is playing an increasingly important role within the fuel industry. Among biofuels, bioethanol has been most widely used as an additive for gasoline. Higher alcohols can be blended at a higher volume compared to ethanol and generate lower greenhouse gas (GHG) emissions without a need to change current fuel infrastructures. Thus, these fuels have the potential to replace fossil fuels in support of more environmentally friendly processes. This review summarizes the efforts to enhance bioalcohol production in engineered Escherichia coli over the last 5 years and analyzes the current challenges for increasing productivities for industrial applications.

Original language	English
Article number	710
Journal	Frontiers in Bioengineering and Biotechnology
Volume	8
DOIs	https://doi.org/10.3389/fbioe.2020.00710
State	Published - Jul 3 2020
Externally published	Yes

Funding

Funding. This project was sponsored by the U.S. Department of Energy (Grant DE-SC0018368) and the Center for Bioenergy Innovation a U.S. Department of Energy Research Center supported by the Office of Biological and Environmental Research in the DOE Office of Science.

Funders	Funder number
Center for Bioenergy Innovation a U.S. Department of Energy Research Center
U.S. Department of Energy	DE-SC0018368
Office of Science
Biological and Environmental Research

Keywords

C2–C6 bioalcohol
Escherichia coli
butanol
ethanol
isobutanol
isopentanol
isopentenol
isopropanol

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3389/fbioe.2020.00710

Cite this

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title = "Synthetic Biology and Metabolic Engineering Employing Escherichia coli for C2–C6 Bioalcohol Production",

abstract = "Biofuel production from renewable and sustainable resources is playing an increasingly important role within the fuel industry. Among biofuels, bioethanol has been most widely used as an additive for gasoline. Higher alcohols can be blended at a higher volume compared to ethanol and generate lower greenhouse gas (GHG) emissions without a need to change current fuel infrastructures. Thus, these fuels have the potential to replace fossil fuels in support of more environmentally friendly processes. This review summarizes the efforts to enhance bioalcohol production in engineered Escherichia coli over the last 5 years and analyzes the current challenges for increasing productivities for industrial applications.",

keywords = "C2–C6 bioalcohol, Escherichia coli, butanol, ethanol, isobutanol, isopentanol, isopentenol, isopropanol",

author = "Liya Liang and Rongming Liu and Freed, {Emily F.} and Eckert, {Carrie A.}",

note = "Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2020 Liang, Liu, Freed and Eckert.",

year = "2020",

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doi = "10.3389/fbioe.2020.00710",

language = "English",

volume = "8",

journal = "Frontiers in Bioengineering and Biotechnology",

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T1 - Synthetic Biology and Metabolic Engineering Employing Escherichia coli for C2–C6 Bioalcohol Production

AU - Liang, Liya

AU - Liu, Rongming

AU - Freed, Emily F.

AU - Eckert, Carrie A.

PY - 2020/7/3

Y1 - 2020/7/3

N2 - Biofuel production from renewable and sustainable resources is playing an increasingly important role within the fuel industry. Among biofuels, bioethanol has been most widely used as an additive for gasoline. Higher alcohols can be blended at a higher volume compared to ethanol and generate lower greenhouse gas (GHG) emissions without a need to change current fuel infrastructures. Thus, these fuels have the potential to replace fossil fuels in support of more environmentally friendly processes. This review summarizes the efforts to enhance bioalcohol production in engineered Escherichia coli over the last 5 years and analyzes the current challenges for increasing productivities for industrial applications.

AB - Biofuel production from renewable and sustainable resources is playing an increasingly important role within the fuel industry. Among biofuels, bioethanol has been most widely used as an additive for gasoline. Higher alcohols can be blended at a higher volume compared to ethanol and generate lower greenhouse gas (GHG) emissions without a need to change current fuel infrastructures. Thus, these fuels have the potential to replace fossil fuels in support of more environmentally friendly processes. This review summarizes the efforts to enhance bioalcohol production in engineered Escherichia coli over the last 5 years and analyzes the current challenges for increasing productivities for industrial applications.

KW - C2–C6 bioalcohol

KW - Escherichia coli

KW - butanol

KW - ethanol

KW - isobutanol

KW - isopentanol

KW - isopentenol

KW - isopropanol

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DO - 10.3389/fbioe.2020.00710

M3 - Review article

AN - SCOPUS:85088439065

SN - 2296-4185

VL - 8

JO - Frontiers in Bioengineering and Biotechnology

JF - Frontiers in Bioengineering and Biotechnology

M1 - 710

ER -

Synthetic Biology and Metabolic Engineering Employing Escherichia coli for C2–C6 Bioalcohol Production

Abstract

Funding

Keywords

UN SDGs

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