TY - JOUR
T1 - Synthesis of N-halamine-functionalized silica-polymer core-shell nanoparticles and their enhanced antibacterial activity
AU - Dong, Alideertu
AU - Huang, Jinfeng
AU - Lan, Shi
AU - Wang, Tao
AU - Xiao, Linghan
AU - Wang, Weiwei
AU - Zhao, Tianyi
AU - Zheng, Xin
AU - Liu, Fengqi
AU - Gao, Ge
AU - Chen, Yuxin
PY - 2011/7/22
Y1 - 2011/7/22
N2 - N-halamine-functionalized silica-polymer core-shell nanoparticles with enhanced antibacterial activity were synthesized through the encapsulation of silica nanoparticles as support with polymeric N-halamine. The as-synthesized nanoparticles were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive x-ray spectrometry (EDX), dynamic light scattering (DLS), thermogravimetric analysis (TGA), and Fourier transform infrared (FTIR). These N-halamine-functionalized silica-polymer core-shell nanoparticles displayed powerful antibacterial performance against both Gram-positive bacteria and Gram-negative bacteria, and their antibacterial activities have been greatly improved compared with their bulk counterparts. Therefore, these N-halamine-functionalized silica-polymer core-shell nanoparticles have the potential for various significant applications such as in medical devices, healthcare products, water purification systems, hospitals, dental office equipment, food packaging, food storage, household sanitation, etc.
AB - N-halamine-functionalized silica-polymer core-shell nanoparticles with enhanced antibacterial activity were synthesized through the encapsulation of silica nanoparticles as support with polymeric N-halamine. The as-synthesized nanoparticles were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive x-ray spectrometry (EDX), dynamic light scattering (DLS), thermogravimetric analysis (TGA), and Fourier transform infrared (FTIR). These N-halamine-functionalized silica-polymer core-shell nanoparticles displayed powerful antibacterial performance against both Gram-positive bacteria and Gram-negative bacteria, and their antibacterial activities have been greatly improved compared with their bulk counterparts. Therefore, these N-halamine-functionalized silica-polymer core-shell nanoparticles have the potential for various significant applications such as in medical devices, healthcare products, water purification systems, hospitals, dental office equipment, food packaging, food storage, household sanitation, etc.
UR - http://www.scopus.com/inward/record.url?scp=79960439021&partnerID=8YFLogxK
U2 - 10.1088/0957-4484/22/29/295602
DO - 10.1088/0957-4484/22/29/295602
M3 - Article
C2 - 21673388
AN - SCOPUS:79960439021
SN - 0957-4484
VL - 22
JO - Nanotechnology
JF - Nanotechnology
IS - 29
M1 - 295602
ER -