Suspended micro-ring resonator for enhanced biomolecule detection sensitivity

Shuren Hu, Kun Qin, Ivan I. Kravchenko, Scott T. Retterer, Sharon M. Weiss

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

13 Scopus citations

Abstract

Silicon micro-ring biosensors demonstrate great potential for high sensitivity and multiplexed lab-on-chip systems. In this work, we characterize the sensing performance of suspended TM-mode silicon micro-ring resonators, 5 μm in radius, and demonstrate an enhanced sensitivity to molecular binding on the ring after suspension. In the TM-mode, the overall field intensity exists primarily outside of the waveguide core, with high electric field intensities present near the top and bottom surfaces. In traditional micro-ring resonators, only the top surface of the ring is available for surface analyte attachment, while the electric field intensity near the bottom surface dissipates by leaking into the underlying silicon dioxide substrate. In our approach, we suspend the TM-micro ring resonators in order to increase the surface area for binding events and increase the light-matter interaction with analytes. The suspended rings demonstrate excellent mechanical stability to multiple rinsing, soaking and nitrogen drying steps during the sensing procedure. We show that the resonance shift achieved by the suspended micro-rings after attachment of small chemical molecules and DNA is at least twice that of micro-rings supported by the silicon dioxide substrate.

Original languageEnglish
Title of host publicationFrontiers in Biological Detection
Subtitle of host publicationFrom Nanosensors to Systems VI
PublisherSPIE
ISBN (Print)9780819498465
DOIs
StatePublished - 2014
EventFrontiers in Biological Detection: From Nanosensors to Systems VI - San Francisco, CA, United States
Duration: Feb 1 2014Feb 2 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8933
ISSN (Print)1605-7422

Conference

ConferenceFrontiers in Biological Detection: From Nanosensors to Systems VI
Country/TerritoryUnited States
CitySan Francisco, CA
Period02/1/1402/2/14

Funding

FundersFunder number
National Science FoundationECCS0746296, EECS0925642
U.S. Department of Energy
National Science Foundation0746296

    Keywords

    • DNA
    • high sensitivity
    • label-free
    • ring resonator
    • sensing
    • suspended

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