Abstract
The use of nanomachining methods capable of reproducible construction of nano-arrayed devices have revolutionized the field of plasmonic sensing by the introduction of a diversity of rationally engineered designs. Significant strides have been made to fabricate plasmonic platforms with tailored interparticle gaps to improve their performance for surface-enhanced Raman scattering (SERS) applications. Over time, a dichotomy has emerged in the implementation of SERS for analytical applications, the construction of substrates, optimization of interparticle spacing as a means to optimize electromagnetic field enhancement at the localized surface plasmon level, and the substrate sensitivity over extended areas to achieve quantitative performance. This work assessed the enhancement factor of plasmonic Ag/SiO2/Si disc-on-pillar (DOP) arrays of variable pitch with its analytical performance for quantitative applications. Experimental data were compared with those from finite-difference time-domain (FDTD) simulations used in the optimization of the array dimensions. A self-assembled monolayer (SAM) of benzenethiol rendered highly reproducible signals (RSD ∼4–10%) and SERS substrate enhancement factor (SSEF) values in the orders of 106–108 for all pitches. Spectra corresponding to rhodamine 6G (R6G) and 4-aminobenzoic acid demonstrated the advantages of using the more densely packed DOP arrays with a 160 nm pitch (gap = 40 nm) for quantitation in spite of the strongest SSEF was attained for a pitch of 520 nm corresponding to a 400 nm gap.
Original language | English |
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Pages (from-to) | 665-677 |
Number of pages | 13 |
Journal | Applied Spectroscopy |
Volume | 73 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2019 |
Funding
RAV acknowledges the support provided by UPRM RISE-2-Best Biomedical Research Program (NIH Grant 1R25GM088023). Fabrication of the nanostructures was conducted at the Center for Nanophase Materials Sciences, which is a DOE Office of Science User Facility. All spectra were acquired either at the University of Tennessee at Knoxville, Tennessee, or at the Analytical Services Laboratory of HP, Inc., at Aguadilla, Puerto Rico.
Funders | Funder number |
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DOE Office of Science user facility | |
UPRM RISE-2-Best Biomedical Research Program | |
National Institutes of Health | 1R25GM088023 |
National Institutes of Health | |
University of Tennessee | |
spectra |
Keywords
- FDTD
- SERS
- SERS substrate enhancement factor
- Surface-enhanced Raman spectroscopy
- calibration sensitivity
- disc-on-pillar
- finite-difference time-domain
- nanofabrication