Abstract
Many features of living systems prevent the application of fundamental statistical mechanics (FSM) to study such systems. The present work focuses on some of these features. After discussing all the basic approaches of FSM, the work formulates an extension of the kinetic theory paradigm (based on the reduced one-particle distribution function) that exhibits all of the living-system properties considered. This extension appears to be a model within the generalized kinetic theory developed by N. Bellomo and his co-authors. In connection with this model, the work also stresses some other features necessary for making the model relevant to living systems. A mathematical formulation of homeorhesis is also derived. An example discussed in the work is a generalized kinetic equation coupled with a probability-density equation representing the varying component content of a living system. The work also suggests a few directions for future research.
Original language | English |
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Pages (from-to) | 595-607 |
Number of pages | 13 |
Journal | Mathematical and Computer Modelling |
Volume | 44 |
Issue number | 7-8 |
DOIs | |
State | Published - Oct 2006 |
Externally published | Yes |
Funding
The present work was partly supported by the Instituto Nazionale di Alta Matematica Francesco Severi (Rome, Italy). The authors thank the European Commission Marie Curie Research Training Network MRTN-CT-2004-503661 “Modelling, Mathematical Methods and Computer Simulation of Tumour Growth and Therapy” ( http://calvino.polito.it/~mcrtn/ ) for the full support of the second author. The authors are very grateful to N. Bellomo, Politecnico di Torino (Turin, Italy), for a series of stimulating and fruitful discussions during the research stay of the first author at Politecnico di Torino in autumn 2005.
Funders | Funder number |
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Istituto Nazionale di Alta Matematica "Francesco Severi" |
Keywords
- Fundamental statistical mechanics
- Generalized kinetic theory
- Homeorhesis
- Living system
- Stochastic process