Spontaneously Formed Unilamellar Vesicles

Mu Ping Nieh; Norbert Kučerka; John Katsaras

doi:10.1016/S0076-6879(09)65001-1

Spontaneously Formed Unilamellar Vesicles

Mu Ping Nieh, Norbert Kučerka, John Katsaras

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

Mixtures of long- and short-chain phospholipids can spontaneously form uniform unilamellar vesicles (ULVs) with diameters 50 nm (polydispersities of <0.3) or less. The morphology of these ULVs has mainly been characterized using small angle neutron scattering (SANS), a technique highly suited for the study of hydrogenous materials. Once formed, these ULVs have turned out to be highly stable and show great promise as imaging and therapeutic carriers.

Original language	English
Pages (from-to)	3-20
Number of pages	18
Journal	Methods in Enzymology
Volume	465
Issue number	C
DOIs	https://doi.org/10.1016/S0076-6879(09)65001-1
State	Published - 2009
Externally published	Yes

Funding

NK would like to acknowledge funding from the Advanced Foods and Materials Network, part of the Networks of Centres of Excellence.

Funders	Funder number
Advanced Foods and Materials Network
Networks of Centres of Excellence of Canada

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10.1016/S0076-6879(09)65001-1

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abstract = "Mixtures of long- and short-chain phospholipids can spontaneously form uniform unilamellar vesicles (ULVs) with diameters 50 nm (polydispersities of <0.3) or less. The morphology of these ULVs has mainly been characterized using small angle neutron scattering (SANS), a technique highly suited for the study of hydrogenous materials. Once formed, these ULVs have turned out to be highly stable and show great promise as imaging and therapeutic carriers.",

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AU - Kučerka, Norbert

AU - Katsaras, John

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AB - Mixtures of long- and short-chain phospholipids can spontaneously form uniform unilamellar vesicles (ULVs) with diameters 50 nm (polydispersities of <0.3) or less. The morphology of these ULVs has mainly been characterized using small angle neutron scattering (SANS), a technique highly suited for the study of hydrogenous materials. Once formed, these ULVs have turned out to be highly stable and show great promise as imaging and therapeutic carriers.

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DO - 10.1016/S0076-6879(09)65001-1

M3 - Review article

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Spontaneously Formed Unilamellar Vesicles

Abstract

Funding

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