Abstract
A dynamic transition at temperatures ∼200-230K is observed in many hydrated biopolymers. It shows up as a sharp increase of the mean-squared atomic displacements above this temperature range. We present neutron scattering data of DNA at different levels of hydration. The analysis shows that the dynamic transition in DNA is related to a slow relaxation process in the MHz-GHz frequency range. This slow relaxation process is completely suppressed in the dry DNA sample where no dynamic transition was observed, The nature of the slow process is discussed, We ascribe it to a global relaxation of DNA molecule that involves cooperative motion of many base-pairs and backbone.
| Original language | English |
|---|---|
| Pages (from-to) | 313-327 |
| Number of pages | 15 |
| Journal | Journal of Biological Physics |
| Volume | 27 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2001 |
| Externally published | Yes |
Funding
The authors are thankful to ILL for assistance in the experiment. APS thanks R. Nossal, D. Sackett, S. Leikin (all from NIH) and A. Tsai (NIST) for many helpful discussions and NIH for hospitality during summer 2000. Financial support from Research Office of the University of Akron is greatly appreciated.
Keywords
- Bio-polymers
- Dynamic transition
- Dynamics
- Influence of hydration
- Relaxation in biopolymers
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