Abstract
Researchers reported the anti-bacterial activity of quaternized poly(L-lactide)-block (PLLA-b)-PDMAEMA block copolymers assembled into spherical particles and diamond-shaped platelets of twodifferent sizes using a crystallization-driven self-assembly (CDSA) approach. H NMR spectroscopic analysis was used to confirm the degree of polymerization and a narrow dispersity of the polymer and monomodal distribution was confirmed by size exclusion chromatography refractive index analysis, with good overlap of the ultraviolet trace showing retention of the RAFT chain transfer agent (CTA) end group. A series of cationically-charged nanostructures were prepared using both CDSA and conventional self-assembly. Diamond-shaped platelets were prepared by heating the polymer in a sealed vial for 4 h before cooling to room temperature and ageing for 1 day. Semicrystalline platelets were formed as confirmed by transmission electron microscopy (TEM) and wide-angle X-ray diffraction analysis.
| Original language | English |
|---|---|
| Pages (from-to) | 255-259 |
| Number of pages | 5 |
| Journal | Journal of Polymer Science, Part A: Polymer Chemistry |
| Volume | 57 |
| Issue number | 3 |
| DOIs | |
| State | Published - Feb 1 2019 |
| Externally published | Yes |
Funding
The authors would like to thank the ERC (615142), EPSRC, Royal Society, and NSFC (21674081) for funding.
| Funders | Funder number |
|---|---|
| Engineering and Physical Sciences Research Council | |
| Royal Society | |
| European Research Council | |
| Seventh Framework Programme | 615142 |
| National Natural Science Foundation of China | 21674081 |
Keywords
- biological activity
- platelets
- polymers
- self-assembly
- size effects