Sensing DNA hybridization via ionic conductance through a nanoporous electrode

Ivan Vlassiouk, Pavel Takmakov, Sergei Smirnov

Research output: Contribution to journalArticlepeer-review

119 Scopus citations

Abstract

We show that nanoporous alumina modified with covalently linked DNA can be used to detect target DNA by monitoring the increase in impedance at the electrode upon DNA hybridization, which resulted from blocking the pores to ionic flow. Using cyclic voltammetry, direct current conductance, and impedance spectroscopy we confirm the importance of pore size: the effect is observed with 20-nm-diameter pores and is absent for 200-nm pores.

Original languageEnglish
Pages (from-to)4776-4778
Number of pages3
JournalLangmuir
Volume21
Issue number11
DOIs
StatePublished - May 24 2005
Externally publishedYes

Fingerprint

Dive into the research topics of 'Sensing DNA hybridization via ionic conductance through a nanoporous electrode'. Together they form a unique fingerprint.

Cite this