Selective perturbation of in vivo linear energy transfer using high-Z vaginal applicators for Cf-252 brachytherapy

M. J. Rivard; K. E. Evans; L. C. Leal; B. L. Kirk

doi:10.1016/S0168-583X(03)01659-8

Selective perturbation of in vivo linear energy transfer using high-Z vaginal applicators for Cf-252 brachytherapy

M. J. Rivard, K. E. Evans, L. C. Leal, B. L. Kirk

Nuclear Data

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

Californium-252 (²⁵²Cf) brachytherapy sources emit both neutrons and photons, and have the potential to vastly improve the current standard-of-practice for brachytherapy. While hydrogenous materials readily attenuate the ²⁵²Cf fission energy neutrons, high-Z materials are utilized to attenuate the ²⁵²Cf gamma-rays. These differences in shielding materials may be exploited when treating with a vaginal applicator to possibly improve patient survival through perturbation of the in vivo linear energy transfer radiation.

Original language	English
Pages (from-to)	621-625
Number of pages	5
Journal	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume	213
DOIs	https://doi.org/10.1016/S0168-583X(03)01659-8
State	Published - Jan 2004
Event	5th Topical Meeting on Industrial Radiation and Radioisotope (IRRMA-V) - Bologna, Italy Duration: Jun 9 2002 → Jun 14 2002

Funding

This work was supported in part by a Research Fund grant provided by the New England Medical Center Hospitals Inc. and through the Summer Physics Research Assistantship Program sponsored by the Tufts-NEMC Department of Radiation Oncology for K.E.E.

Keywords

Cf
Brachytherapy
Monte Carlo
Shielding material

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10.1016/S0168-583X(03)01659-8

Cite this

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title = "Selective perturbation of in vivo linear energy transfer using high-Z vaginal applicators for Cf-252 brachytherapy",

abstract = "Californium-252 (252Cf) brachytherapy sources emit both neutrons and photons, and have the potential to vastly improve the current standard-of-practice for brachytherapy. While hydrogenous materials readily attenuate the 252Cf fission energy neutrons, high-Z materials are utilized to attenuate the 252Cf gamma-rays. These differences in shielding materials may be exploited when treating with a vaginal applicator to possibly improve patient survival through perturbation of the in vivo linear energy transfer radiation.",

keywords = "Cf, Brachytherapy, Monte Carlo, Shielding material",

author = "Rivard, \{M. J.\} and Evans, \{K. E.\} and Leal, \{L. C.\} and Kirk, \{B. L.\}",

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doi = "10.1016/S0168-583X(03)01659-8",

language = "English",

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journal = "Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms",

issn = "0168-583X",

publisher = "Elsevier",

note = "5th Topical Meeting on Industrial Radiation and Radioisotope (IRRMA-V) ; Conference date: 09-06-2002 Through 14-06-2002",

}

Selective perturbation of in vivo linear energy transfer using high-Z vaginal applicators for Cf-252 brachytherapy. / Rivard, M. J.; Evans, K. E.; Leal, L. C. et al.
In: Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, Vol. 213, 01.2004, p. 621-625.

Research output: Contribution to journal › Conference article › peer-review

TY - JOUR

T1 - Selective perturbation of in vivo linear energy transfer using high-Z vaginal applicators for Cf-252 brachytherapy

AU - Rivard, M. J.

AU - Evans, K. E.

AU - Leal, L. C.

AU - Kirk, B. L.

PY - 2004/1

Y1 - 2004/1

N2 - Californium-252 (252Cf) brachytherapy sources emit both neutrons and photons, and have the potential to vastly improve the current standard-of-practice for brachytherapy. While hydrogenous materials readily attenuate the 252Cf fission energy neutrons, high-Z materials are utilized to attenuate the 252Cf gamma-rays. These differences in shielding materials may be exploited when treating with a vaginal applicator to possibly improve patient survival through perturbation of the in vivo linear energy transfer radiation.

AB - Californium-252 (252Cf) brachytherapy sources emit both neutrons and photons, and have the potential to vastly improve the current standard-of-practice for brachytherapy. While hydrogenous materials readily attenuate the 252Cf fission energy neutrons, high-Z materials are utilized to attenuate the 252Cf gamma-rays. These differences in shielding materials may be exploited when treating with a vaginal applicator to possibly improve patient survival through perturbation of the in vivo linear energy transfer radiation.

KW - Cf

KW - Brachytherapy

KW - Monte Carlo

KW - Shielding material

UR - https://www.scopus.com/pages/publications/0242410588

U2 - 10.1016/S0168-583X(03)01659-8

DO - 10.1016/S0168-583X(03)01659-8

M3 - Conference article

AN - SCOPUS:0242410588

SN - 0168-583X

VL - 213

SP - 621

EP - 625

JO - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

JF - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

T2 - 5th Topical Meeting on Industrial Radiation and Radioisotope (IRRMA-V)

Y2 - 9 June 2002 through 14 June 2002

ER -

Selective perturbation of in vivo linear energy transfer using high-Z vaginal applicators for Cf-252 brachytherapy

Abstract

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Keywords

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