Abstract
Recognition of (thio)sulfate and phosphate in aqueous solutions has been demonstrated by using oligo-urea-based receptors functionalized with quaternary ammonium groups. The ammonium groups allow for increased aqueous solubility while simultaneously providing positive coulombic interactions and stronger hydrogen bonding through an inductive effect. This simple and generally applicable modification provides an effective way to bolster the anion binding and water solubility of oligo-urea-based receptors. With a water soluble receptor 2, selective binding of adenosine phosphates was achieved at physiological pH.
| Original language | English |
|---|---|
| Pages (from-to) | 1714-1717 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 55 |
| Issue number | 12 |
| DOIs | |
| State | Published - 2019 |
Funding
Z. H. and C. J. are grateful for the financial support of the National Natural Science Foundation of China (21701132), and the Education Department of Shaanxi (16JS113). The research at Oak Ridge National Laboratory, including receptors syntheses, binding studies, and X-ray structural determination, was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, Chemical Sciences, Geosciences, and Biosciences Division.
| Funders | Funder number |
|---|---|
| U.S. Department of Energy | |
| Office of Science | |
| Basic Energy Sciences | |
| Oak Ridge National Laboratory | |
| Chemical Sciences, Geosciences, and Biosciences Division | |
| National Natural Science Foundation of China | 21701132 |
| Education Department of Shaanxi Province | 16JS113 |