Secondary metabolism in Penicillium expansum: Emphasis on recent advances in patulin research

Joanna Tannous; Nancy P. Keller; Ali Atoui; André El Khoury; Roger Lteif; Isabelle P. Oswald; Olivier Puel

doi:10.1080/10408398.2017.1305945

Secondary metabolism in Penicillium expansum: Emphasis on recent advances in patulin research

Joanna Tannous, Nancy P. Keller, Ali Atoui, André El Khoury, Roger Lteif, Isabelle P. Oswald, Olivier Puel

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

The plant pathogenic fungus Penicillium expansum is a major concern of the global food industry due to its wide occurrence and ability to produce various mycotoxins, of which the most significant is patulin. Relatively less highlighted in the literature, in comparison with the other food-borne mycotoxins, patulin is one of the main factors in economic losses of vegetables and fruits. Otherwise, patulin is a health hazard which results in both short-term and long-term risks. This review includes knowledge on the biosynthetic mechanisms used for secondary metabolite production in P. expansum, with special emphasis on patulin biosynthesis. The abiotic factors triggering the production of patulin and the strategies developed to reduce or prevent the contamination by this mycotoxin are comprehensively discussed. The database presented in this review would be useful for the prioritization and development of future research.

Original language	English
Pages (from-to)	2082-2098
Number of pages	17
Journal	Critical Reviews in Food Science and Nutrition
Volume	58
Issue number	12
DOIs	https://doi.org/10.1080/10408398.2017.1305945
State	Published - Aug 13 2018
Externally published	Yes

Funding

This review paper is based upon work supported by the National Council for Scientific Research (CNRS), Lebanon under Grant 3443; the Research Council of Saint-Joseph University (Lebanon) under Grant FS38; and CASDAR AAP RT 2015 under Grant 1523, project “Mycotoxines majeures et émergentes dans les filières cidre et vin.” This review paper is based upon work supported by the National Council for Scientific Research (CNRS), Lebanon under Grant 3443; the Research Council of Saint- Joseph University (Lebanon) under Grant FS38; and CASDAR AAP RT 2015 under Grant 1523, project ?Mycotoxines majeures et ?mergentes dans les fili?res cidre et vin.?

Funders	Funder number
College of Natural Resources and Sciences, Humboldt State University	3443
National Research Council
Saint Joseph University
the Research Council of Saint-Joseph University	1523, FS38, CASDAR AAP RT 2015

Keywords

Penicillium expansum
apples
biosynthesis
pathogenicity determinants
patulin
secondary metabolites

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10.1080/10408398.2017.1305945

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title = "Secondary metabolism in Penicillium expansum: Emphasis on recent advances in patulin research",

abstract = "The plant pathogenic fungus Penicillium expansum is a major concern of the global food industry due to its wide occurrence and ability to produce various mycotoxins, of which the most significant is patulin. Relatively less highlighted in the literature, in comparison with the other food-borne mycotoxins, patulin is one of the main factors in economic losses of vegetables and fruits. Otherwise, patulin is a health hazard which results in both short-term and long-term risks. This review includes knowledge on the biosynthetic mechanisms used for secondary metabolite production in P. expansum, with special emphasis on patulin biosynthesis. The abiotic factors triggering the production of patulin and the strategies developed to reduce or prevent the contamination by this mycotoxin are comprehensively discussed. The database presented in this review would be useful for the prioritization and development of future research.",

keywords = "Penicillium expansum, apples, biosynthesis, pathogenicity determinants, patulin, secondary metabolites",

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doi = "10.1080/10408398.2017.1305945",

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T2 - Emphasis on recent advances in patulin research

AU - Tannous, Joanna

AU - Keller, Nancy P.

AU - Atoui, Ali

AU - El Khoury, André

AU - Lteif, Roger

AU - Oswald, Isabelle P.

AU - Puel, Olivier

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AB - The plant pathogenic fungus Penicillium expansum is a major concern of the global food industry due to its wide occurrence and ability to produce various mycotoxins, of which the most significant is patulin. Relatively less highlighted in the literature, in comparison with the other food-borne mycotoxins, patulin is one of the main factors in economic losses of vegetables and fruits. Otherwise, patulin is a health hazard which results in both short-term and long-term risks. This review includes knowledge on the biosynthetic mechanisms used for secondary metabolite production in P. expansum, with special emphasis on patulin biosynthesis. The abiotic factors triggering the production of patulin and the strategies developed to reduce or prevent the contamination by this mycotoxin are comprehensively discussed. The database presented in this review would be useful for the prioritization and development of future research.

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Secondary metabolism in Penicillium expansum: Emphasis on recent advances in patulin research

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Keywords

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