Abstract
DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.
| Original language | English |
|---|---|
| Pages (from-to) | 335-336 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series (2004) |
| Issue number | 51 |
| DOIs | |
| State | Published - 2007 |
| Externally published | Yes |