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SAXS measurement of aggregate of DNA modified gold nanoparticles.

  • Shizuto Yamakoshi
  • , Yasuhiro Sakai
  • , Yuya Shinohara
  • , Yoshiyuki Amemiya
  • , Naoki Kanayama
  • , Tohru Takarada
  • , Mizuo Maeda
  • , Kohzo Ito

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.

Original languageEnglish
Pages (from-to)335-336
Number of pages2
JournalNucleic acids symposium series (2004)
Issue number51
DOIs
StatePublished - 2007
Externally publishedYes

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