SAXS measurement of aggregate of DNA modified gold nanoparticles.

Shizuto Yamakoshi; Yasuhiro Sakai; Yuya Shinohara; Yoshiyuki Amemiya; Naoki Kanayama; Tohru Takarada; Mizuo Maeda; Kohzo Ito

doi:10.1093/nass/nrm168

SAXS measurement of aggregate of DNA modified gold nanoparticles.

Shizuto Yamakoshi, Yasuhiro Sakai, Yuya Shinohara, Yoshiyuki Amemiya, Naoki Kanayama, Tohru Takarada, Mizuo Maeda, Kohzo Ito

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.

Original language	English
Pages (from-to)	335-336
Number of pages	2
Journal	Nucleic acids symposium series (2004)
Issue number	51
DOIs	https://doi.org/10.1093/nass/nrm168
State	Published - 2007
Externally published	Yes

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title = "SAXS measurement of aggregate of DNA modified gold nanoparticles.",

abstract = "DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.",

author = "Shizuto Yamakoshi and Yasuhiro Sakai and Yuya Shinohara and Yoshiyuki Amemiya and Naoki Kanayama and Tohru Takarada and Mizuo Maeda and Kohzo Ito",

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T1 - SAXS measurement of aggregate of DNA modified gold nanoparticles.

AU - Yamakoshi, Shizuto

AU - Sakai, Yasuhiro

AU - Shinohara, Yuya

AU - Amemiya, Yoshiyuki

AU - Kanayama, Naoki

AU - Takarada, Tohru

AU - Maeda, Mizuo

AU - Ito, Kohzo

PY - 2007

Y1 - 2007

N2 - DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.

AB - DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.

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U2 - 10.1093/nass/nrm168

DO - 10.1093/nass/nrm168

M3 - Article

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SP - 335

EP - 336

JO - Nucleic acids symposium series (2004)

JF - Nucleic acids symposium series (2004)

IS - 51

ER -

SAXS measurement of aggregate of DNA modified gold nanoparticles.

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