Review of Technical Advancements and Clinical Applications of Photon-counting Computed Tomography in Imaging of the Thorax

Faraz Farhadi; Jayasai R. Rajagopal; Moozhan Nikpanah; Pooyan Sahbaee; Ashkan A. Malayeri; William F. Pritchard; Ehsan Samei; Elizabeth C. Jones; Marcus Y. Chen

doi:10.1097/RTI.0000000000000569

Review of Technical Advancements and Clinical Applications of Photon-counting Computed Tomography in Imaging of the Thorax

Faraz Farhadi, Jayasai R. Rajagopal, Moozhan Nikpanah, Pooyan Sahbaee, Ashkan A. Malayeri, William F. Pritchard, Ehsan Samei, Elizabeth C. Jones, Marcus Y. Chen

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

Photon-counting computed tomography (CT) is a developing technology that has the potential to address some limitations of CT imaging and bring about improvements and potentially new applications to this field. Photon-counting detectors have a fundamentally different detection mechanism from conventional CT energy-integrating detectors that can improve dose efficiency, spatial resolution, and energy-discrimination capabilities. In the past decade, promising human studies have been reported in the literature that have demonstrated benefits of this relatively new technology for various clinical applications. In this review, we provide a succinct description of the photon-counting detector technology and its detection mechanism in comparison with energy-integrating detectors in a manner understandable for clinicians and radiologists, introduce benefits and some of the existing challenges present in this technology, and provide an overview of the current status and potential clinical applications of this technology in imaging of the thorax by providing example images acquired with an investigational whole-body photon-counting CT scanner.

Original language	English
Pages (from-to)	84-94
Number of pages	11
Journal	Journal of Thoracic Imaging
Volume	36
Issue number	2
DOIs	https://doi.org/10.1097/RTI.0000000000000569
State	Published - Mar 2021
Externally published	Yes

Funding

This research was supported, in part, by the Intramural Research Pro-gram of the National Institutes of Health Clinical Center. The National Institutes of Health and Siemens Medical Solutions have a Cooperative Research and Development Agreement providing financial and material support including the photon-counting CT system. Authors unaffiliated with Siemens had full control over data and information presented in this paper. The clinical images were acquired under a protocol approved by the Institutional Review Board using an investigational photon-counting computed tomog-raphy system.

Keywords

photon-counting computed tomography
spectral computed tomography
thoracic imaging

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10.1097/RTI.0000000000000569

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title = "Review of Technical Advancements and Clinical Applications of Photon-counting Computed Tomography in Imaging of the Thorax",

abstract = "Photon-counting computed tomography (CT) is a developing technology that has the potential to address some limitations of CT imaging and bring about improvements and potentially new applications to this field. Photon-counting detectors have a fundamentally different detection mechanism from conventional CT energy-integrating detectors that can improve dose efficiency, spatial resolution, and energy-discrimination capabilities. In the past decade, promising human studies have been reported in the literature that have demonstrated benefits of this relatively new technology for various clinical applications. In this review, we provide a succinct description of the photon-counting detector technology and its detection mechanism in comparison with energy-integrating detectors in a manner understandable for clinicians and radiologists, introduce benefits and some of the existing challenges present in this technology, and provide an overview of the current status and potential clinical applications of this technology in imaging of the thorax by providing example images acquired with an investigational whole-body photon-counting CT scanner.",

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author = "Faraz Farhadi and Rajagopal, {Jayasai R.} and Moozhan Nikpanah and Pooyan Sahbaee and Malayeri, {Ashkan A.} and Pritchard, {William F.} and Ehsan Samei and Jones, {Elizabeth C.} and Chen, {Marcus Y.}",

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AU - Rajagopal, Jayasai R.

AU - Nikpanah, Moozhan

AU - Sahbaee, Pooyan

AU - Malayeri, Ashkan A.

AU - Pritchard, William F.

AU - Samei, Ehsan

AU - Jones, Elizabeth C.

AU - Chen, Marcus Y.

PY - 2021/3

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AB - Photon-counting computed tomography (CT) is a developing technology that has the potential to address some limitations of CT imaging and bring about improvements and potentially new applications to this field. Photon-counting detectors have a fundamentally different detection mechanism from conventional CT energy-integrating detectors that can improve dose efficiency, spatial resolution, and energy-discrimination capabilities. In the past decade, promising human studies have been reported in the literature that have demonstrated benefits of this relatively new technology for various clinical applications. In this review, we provide a succinct description of the photon-counting detector technology and its detection mechanism in comparison with energy-integrating detectors in a manner understandable for clinicians and radiologists, introduce benefits and some of the existing challenges present in this technology, and provide an overview of the current status and potential clinical applications of this technology in imaging of the thorax by providing example images acquired with an investigational whole-body photon-counting CT scanner.

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Review of Technical Advancements and Clinical Applications of Photon-counting Computed Tomography in Imaging of the Thorax

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