Responsive polymeric micelles for drug delivery applications/cancer therapy

Panagiota G. Fragouli; Dimitra Stavroulaki; Panagiotis Christakopoulos; Varvara Athanasiou; Maria Kasimati; Katerina Mathianaki; Hermis Iatrou

doi:10.1016/B978-0-08-101995-5.00018-0

Responsive polymeric micelles for drug delivery applications/cancer therapy

Panagiota G. Fragouli
, Dimitra Stavroulaki
, Panagiotis Christakopoulos
, Varvara Athanasiou
, Maria Kasimati
, Katerina Mathianaki
, Hermis Iatrou

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

In this chapter, we highlight the recent progress in the synthesis of well-defined polymers that self-assemble into micelles in aqueous solutions, and which have been loaded with anticancer drugs and studied for their functionality. Initially, we describe the synthesis of pH-responsive polymeric materials, and their study through in vitro and in vivo tests. Then we report the thermo-, redox-, magnetic-responsive micelle carrying anticancer agents. Finally, we present the multiresponsive and the nanocarriers bearing surface markers to target cancer cells. A short description has been given for the biological results of these nanocarriers. In this chapter, we cover all the main stimuli-responsive functionalities of the most recent literature.

Original language	English
Title of host publication	Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications
Subtitle of host publication	Volume 2: Advanced Nanocarriers for Therapeutics
Publisher	Elsevier
Pages	439-460
Number of pages	22
ISBN (Electronic)	9780081019955
ISBN (Print)	9780081019962
DOIs	https://doi.org/10.1016/B978-0-08-101995-5.00018-0
State	Published - Jan 1 2018
Externally published	Yes

Keywords

Anticancer drugs
Cancer
Drug delivery
In vitro
In vivo
Micelles
Polymeric nanocarriers
Polypeptides
Stimuli-responsive

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10.1016/B978-0-08-101995-5.00018-0

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Fragouli, P. G., Stavroulaki, D., Christakopoulos, P., Athanasiou, V., Kasimati, M., Mathianaki, K., & Iatrou, H. (2018). Responsive polymeric micelles for drug delivery applications/cancer therapy. In Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume 2: Advanced Nanocarriers for Therapeutics (pp. 439-460). Elsevier. https://doi.org/10.1016/B978-0-08-101995-5.00018-0

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title = "Responsive polymeric micelles for drug delivery applications/cancer therapy",

abstract = "In this chapter, we highlight the recent progress in the synthesis of well-defined polymers that self-assemble into micelles in aqueous solutions, and which have been loaded with anticancer drugs and studied for their functionality. Initially, we describe the synthesis of pH-responsive polymeric materials, and their study through in vitro and in vivo tests. Then we report the thermo-, redox-, magnetic-responsive micelle carrying anticancer agents. Finally, we present the multiresponsive and the nanocarriers bearing surface markers to target cancer cells. A short description has been given for the biological results of these nanocarriers. In this chapter, we cover all the main stimuli-responsive functionalities of the most recent literature.",

keywords = "Anticancer drugs, Cancer, Drug delivery, In vitro, In vivo, Micelles, Polymeric nanocarriers, Polypeptides, Stimuli-responsive",

author = "Fragouli, \{Panagiota G.\} and Dimitra Stavroulaki and Panagiotis Christakopoulos and Varvara Athanasiou and Maria Kasimati and Katerina Mathianaki and Hermis Iatrou",

year = "2018",

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doi = "10.1016/B978-0-08-101995-5.00018-0",

language = "English",

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Fragouli, PG, Stavroulaki, D, Christakopoulos, P, Athanasiou, V, Kasimati, M, Mathianaki, K & Iatrou, H 2018, Responsive polymeric micelles for drug delivery applications/cancer therapy. in Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume 2: Advanced Nanocarriers for Therapeutics. Elsevier, pp. 439-460. https://doi.org/10.1016/B978-0-08-101995-5.00018-0

Responsive polymeric micelles for drug delivery applications/cancer therapy. / Fragouli, Panagiota G.; Stavroulaki, Dimitra; Christakopoulos, Panagiotis et al.
Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume 2: Advanced Nanocarriers for Therapeutics. Elsevier, 2018. p. 439-460.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Responsive polymeric micelles for drug delivery applications/cancer therapy

AU - Fragouli, Panagiota G.

AU - Stavroulaki, Dimitra

AU - Christakopoulos, Panagiotis

AU - Athanasiou, Varvara

AU - Kasimati, Maria

AU - Mathianaki, Katerina

AU - Iatrou, Hermis

PY - 2018/1/1

Y1 - 2018/1/1

N2 - In this chapter, we highlight the recent progress in the synthesis of well-defined polymers that self-assemble into micelles in aqueous solutions, and which have been loaded with anticancer drugs and studied for their functionality. Initially, we describe the synthesis of pH-responsive polymeric materials, and their study through in vitro and in vivo tests. Then we report the thermo-, redox-, magnetic-responsive micelle carrying anticancer agents. Finally, we present the multiresponsive and the nanocarriers bearing surface markers to target cancer cells. A short description has been given for the biological results of these nanocarriers. In this chapter, we cover all the main stimuli-responsive functionalities of the most recent literature.

AB - In this chapter, we highlight the recent progress in the synthesis of well-defined polymers that self-assemble into micelles in aqueous solutions, and which have been loaded with anticancer drugs and studied for their functionality. Initially, we describe the synthesis of pH-responsive polymeric materials, and their study through in vitro and in vivo tests. Then we report the thermo-, redox-, magnetic-responsive micelle carrying anticancer agents. Finally, we present the multiresponsive and the nanocarriers bearing surface markers to target cancer cells. A short description has been given for the biological results of these nanocarriers. In this chapter, we cover all the main stimuli-responsive functionalities of the most recent literature.

KW - Anticancer drugs

KW - Cancer

KW - Drug delivery

KW - In vitro

KW - In vivo

KW - Micelles

KW - Polymeric nanocarriers

KW - Polypeptides

KW - Stimuli-responsive

UR - https://www.scopus.com/pages/publications/85080820177

U2 - 10.1016/B978-0-08-101995-5.00018-0

DO - 10.1016/B978-0-08-101995-5.00018-0

M3 - Chapter

AN - SCOPUS:85080820177

SN - 9780081019962

SP - 439

EP - 460

BT - Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

PB - Elsevier

ER -

Responsive polymeric micelles for drug delivery applications/cancer therapy

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Keywords

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