Responsive nanoassemblies via interpolyelectrolyte complexation of amphiphilic block copolymer micelles

Brad S. Lokitz; Anthony J. Convertine; Ryan G. Ezell; Andrew Heidenreich; Yuting Li; Charles L. McCormick

doi:10.1021/ma061672y

Responsive nanoassemblies via interpolyelectrolyte complexation of amphiphilic block copolymer micelles

Brad S. Lokitz, Anthony J. Convertine, Ryan G. Ezell, Andrew Heidenreich, Yuting Li, Charles L. McCormick

Research output: Contribution to journal › Article › peer-review

130 Scopus citations

Abstract

Shell "locked" nanoassemblies ranging in size from 34 to 78 nm have been prepared from interpolyelectrolyte complexation of block copolymer micelles of poly[(N,N-dimethylacrylamide)-b-(N-acryloylalanine)-b-(N- isopropylacrylamide)] with the homopolymer poly(ar-vinylbenzyl)trimethylammonium chloride above the unimer to micelle phase transition temperature of the block copolymer in water. Of technological significance is the reversibility of the shell cross-linking by addition of 0.4 M NaCl, allowing micelle dissociation below the lower critical solution temperature of the copolymer micelles. Poly(N-acryloylalanine) (AAL) and block copolymers were prepared directly in water via controlled reversible addition fragmentation chain transfer (RAFT) polymerization utilizing mono- and difunctional poly(N,N-dimethylacrylamide) macroCTAs.

Original language	English
Pages (from-to)	8594-8602
Number of pages	9
Journal	Macromolecules
Volume	39
Issue number	25
DOIs	https://doi.org/10.1021/ma061672y
State	Published - Dec 12 2006
Externally published	Yes

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title = "Responsive nanoassemblies via interpolyelectrolyte complexation of amphiphilic block copolymer micelles",

abstract = "Shell {"}locked{"} nanoassemblies ranging in size from 34 to 78 nm have been prepared from interpolyelectrolyte complexation of block copolymer micelles of poly[(N,N-dimethylacrylamide)-b-(N-acryloylalanine)-b-(N- isopropylacrylamide)] with the homopolymer poly(ar-vinylbenzyl)trimethylammonium chloride above the unimer to micelle phase transition temperature of the block copolymer in water. Of technological significance is the reversibility of the shell cross-linking by addition of 0.4 M NaCl, allowing micelle dissociation below the lower critical solution temperature of the copolymer micelles. Poly(N-acryloylalanine) (AAL) and block copolymers were prepared directly in water via controlled reversible addition fragmentation chain transfer (RAFT) polymerization utilizing mono- and difunctional poly(N,N-dimethylacrylamide) macroCTAs.",

author = "Lokitz, {Brad S.} and Convertine, {Anthony J.} and Ezell, {Ryan G.} and Andrew Heidenreich and Yuting Li and McCormick, {Charles L.}",

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T1 - Responsive nanoassemblies via interpolyelectrolyte complexation of amphiphilic block copolymer micelles

AU - Lokitz, Brad S.

AU - Convertine, Anthony J.

AU - Ezell, Ryan G.

AU - Heidenreich, Andrew

AU - Li, Yuting

AU - McCormick, Charles L.

PY - 2006/12/12

Y1 - 2006/12/12

N2 - Shell "locked" nanoassemblies ranging in size from 34 to 78 nm have been prepared from interpolyelectrolyte complexation of block copolymer micelles of poly[(N,N-dimethylacrylamide)-b-(N-acryloylalanine)-b-(N- isopropylacrylamide)] with the homopolymer poly(ar-vinylbenzyl)trimethylammonium chloride above the unimer to micelle phase transition temperature of the block copolymer in water. Of technological significance is the reversibility of the shell cross-linking by addition of 0.4 M NaCl, allowing micelle dissociation below the lower critical solution temperature of the copolymer micelles. Poly(N-acryloylalanine) (AAL) and block copolymers were prepared directly in water via controlled reversible addition fragmentation chain transfer (RAFT) polymerization utilizing mono- and difunctional poly(N,N-dimethylacrylamide) macroCTAs.

AB - Shell "locked" nanoassemblies ranging in size from 34 to 78 nm have been prepared from interpolyelectrolyte complexation of block copolymer micelles of poly[(N,N-dimethylacrylamide)-b-(N-acryloylalanine)-b-(N- isopropylacrylamide)] with the homopolymer poly(ar-vinylbenzyl)trimethylammonium chloride above the unimer to micelle phase transition temperature of the block copolymer in water. Of technological significance is the reversibility of the shell cross-linking by addition of 0.4 M NaCl, allowing micelle dissociation below the lower critical solution temperature of the copolymer micelles. Poly(N-acryloylalanine) (AAL) and block copolymers were prepared directly in water via controlled reversible addition fragmentation chain transfer (RAFT) polymerization utilizing mono- and difunctional poly(N,N-dimethylacrylamide) macroCTAs.

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Responsive nanoassemblies via interpolyelectrolyte complexation of amphiphilic block copolymer micelles

Abstract

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