Reductive transformation of methyl parathion by the cyanobacterium Anabaena sp. strain PCC7120

J. W. Barton; T. Kuritz; L. E. O'Connor; C. Y. Ma; M. P. Maskarinec; B. H. Davison

doi:10.1007/s00253-004-1557-y

Reductive transformation of methyl parathion by the cyanobacterium Anabaena sp. strain PCC7120

J. W. Barton, T. Kuritz, L. E. O'Connor, C. Y. Ma, M. P. Maskarinec, B. H. Davison

Biosciences Division

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49 Scopus citations

Abstract

Organophosphorus compounds are toxic chemicals that are applied worldwide as household pesticides and for crop protection, and they are stockpiled for chemical warfare. As a result, they are routinely detected in air and water. Methods and routes of biodegradation of these compounds are being sought. We report that under aerobic, photosynthetic conditions, the cyanobacterium Anabaena sp. transformed methyl parathion first to o,o-dimethyl o-p-nitrosophenyl thiophosphate and then to o,o-dimethyl o-p-aminophenyl thiophosphate by reducing the nitro group. The process of methyl parathion transformation occurred in the light, but not in the dark. Methyl parathion was toxic to cyanobacteria in the dark but did not affect their viability in the light. Methyl parathion transformation was not affected by mutations in the genes involved in nitrate reduction in cyanobacteria.

Original language	English
Pages (from-to)	330-335
Number of pages	6
Journal	Applied Microbiology and Biotechnology
Volume	65
Issue number	3
DOIs	https://doi.org/10.1007/s00253-004-1557-y
State	Published - Aug 2004

Funding

Acknowledgements The authors thank L. Renee Rodgers, Alexander Francisco, and K. Thomas Klasson for technical assistance, and Elizabeth T. Owens for reviewing the manuscript. This research was supported by ORNL Laboratory-Directed Research and Development Program. ORNL is managed by UT-Battelle, LLC for the US Department of Energy under contract DE-AC05-00OR22725.

Funders	Funder number
ORNL Laboratory Research and Development Program
U.S. Department of Energy	DE-AC05-00OR22725
Oak Ridge National Laboratory

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AU - Kuritz, T.

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Reductive transformation of methyl parathion by the cyanobacterium Anabaena sp. strain PCC7120

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