TY - GEN
T1 - Reconstruction of high-resolution, multi-energy, x-ray computed tomography laboratory mouse images
AU - Gleason, S. S.
AU - Sari-Sarraf, H.
AU - Paulus, M. J.
AU - Johnson, D. K.
AU - Norton, S. J.
AU - Abidi, M. A.
PY - 1999
Y1 - 1999
N2 - A new x-ray computed tomography system is being developed at the Oak Ridge National Laboratory to image laboratory mice for the purpose of phenotype screening and identification. This CT system allows simultaneous capture of several sets of sinograms data, each having a unique x-ray energy distribution, or bin. Due to varying numbers of photon counts within each energy bin, both traditional (filtered backprojection, or FBP) and statistical (maximum likelihood or ML) tomographic image reconstruction techniques have been applied to the energy-dependent sinogram data. Comparisons of reconstructed images using both algorithms on multi-energy (both high- and low-count) sinogram data are presented. Also, tissue contrast within the energy-dependent images is compared to known x-ray attenuation coefficients of soft tissue (e.g. muscle), bone, and fat.
AB - A new x-ray computed tomography system is being developed at the Oak Ridge National Laboratory to image laboratory mice for the purpose of phenotype screening and identification. This CT system allows simultaneous capture of several sets of sinograms data, each having a unique x-ray energy distribution, or bin. Due to varying numbers of photon counts within each energy bin, both traditional (filtered backprojection, or FBP) and statistical (maximum likelihood or ML) tomographic image reconstruction techniques have been applied to the energy-dependent sinogram data. Comparisons of reconstructed images using both algorithms on multi-energy (both high- and low-count) sinogram data are presented. Also, tissue contrast within the energy-dependent images is compared to known x-ray attenuation coefficients of soft tissue (e.g. muscle), bone, and fat.
UR - http://www.scopus.com/inward/record.url?scp=0032596156&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0032596156
SN - 0780350227
T3 - IEEE Nuclear Science Symposium and Medical Imaging Conference
SP - 1358
EP - 1362
BT - IEEE Nuclear Science Symposium and Medical Imaging Conference
PB - IEEE
T2 - Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record
Y2 - 8 November 1998 through 14 November 1998
ER -