Reconstructing Hanford worker external doses from photons for epidemiology

Michael B. Bellamy, Helen A. Grogan, David Girardi, Sara C. Howard, Ashley P. Golden, Caleigh E. Samuels, Lawrence T. Dauer

Research output: Contribution to journalArticlepeer-review

Abstract

The accurate reconstruction of external photon doses is essential for credible radiation epidemiology. This article presents the methodology used to derive dose estimates for 37 012 Hanford Site workers included in the Million Person Study. The approach employs historical dose records from the Hanford Radiation Exposure database and a previous epidemiology study. Bias correction factors specific to dosimeter type and period of use were applied and missing annual doses were estimated using a hierarchical nearby method to estimate deep dose equivalent for each worker. For early years with limited detection sensitivity, missed doses were quantified based on expected time-period-specific, low-dose statistical distributions. The revised dose estimates resulted in lower median and mean career doses than unadjusted data, while increasing the number of person-years with nonzero dose. Sensitivity analyses assessed the influence of bias in dosimetry measurements, missed doses and gap years on dose estimates. Differences in cumulative dose estimates between unadjusted and revised annual estimates are most prominent in the early operational years due to the highest bias during that time period.

Original languageEnglish
Article number041501
JournalJournal of Radiological Protection
Volume45
Issue number4
DOIs
StatePublished - Dec 1 2025

Funding

This work is a component of the Million Person Study, that was supported in part by a research grant from the U.S. Department of Energy (DOE) (Grant No. DE-SC0008944) awarded to the National Council on Radiation Protection and Measurements, which included interagency support from the U.S. Nuclear Regulatory Commission (NRC), the U.S. Environmental Protection Agency and the National Aeronautics and Space Administration (NASA)); and more recent DOE Grants (Nos. DE-AU0000042 and DE-AU0000046). Additional support included Grants from the NRC (NRC-HQ‐60‐14‐G‐0011); the Centers for Disease Control and Prevention (5UE1EH000989, 5NUE1EH001315); NASA (NNX15AU88G, 80NSSC17M0016, 80NSSC17M0016, 80NSSC19M0161), and a Discovery Grant from the Vanderbilt-lngram Cancer Center (Center No. 404-357-9682). Additional support was received from an NIH/NCI Cancer Center Support Grant (P30 CA008748) awarded to Sloan-Kettering Institute for Cancer Research. Contract support also was received from the Naval Sea Systems Command (N00024-17-C-4322) for dosimetry linkage.

Keywords

  • dose reconstruction
  • dosimetry
  • epidemiology
  • missed dose
  • occupational exposure

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