Raman spectroscopy and neuroscience: From fundamental understanding to disease diagnostics and imaging

Taylor D. Payne; Amber S. Moody; Avery L. Wood; Paula A. Pimiento; James C. Elliott; Bhavya Sharma

doi:10.1039/d0an00083c

Raman spectroscopy and neuroscience: From fundamental understanding to disease diagnostics and imaging

Taylor D. Payne
, Amber S. Moody
, Avery L. Wood
, Paula A. Pimiento
, James C. Elliott
, Bhavya Sharma

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexpensive instrumentation, minimal sample preparation, and rapid sample analysis. This review summarizes Raman spectroscopy-based techniques that have been used to advance the field of neuroscience in recent years.

Original language	English
Pages (from-to)	3461-3480
Number of pages	20
Journal	Analyst
Volume	145
Issue number	10
DOIs	https://doi.org/10.1039/d0an00083c
State	Published - May 21 2020
Externally published	Yes

Funding

The authors thank the University of Tennessee for funding.

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10.1039/d0an00083c

Cite this

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abstract = "Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexpensive instrumentation, minimal sample preparation, and rapid sample analysis. This review summarizes Raman spectroscopy-based techniques that have been used to advance the field of neuroscience in recent years.",

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AU - Elliott, James C.

AU - Sharma, Bhavya

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AB - Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexpensive instrumentation, minimal sample preparation, and rapid sample analysis. This review summarizes Raman spectroscopy-based techniques that have been used to advance the field of neuroscience in recent years.

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Raman spectroscopy and neuroscience: From fundamental understanding to disease diagnostics and imaging

Abstract

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