Raman spectroscopy and neuroscience: From fundamental understanding to disease diagnostics and imaging

Taylor D. Payne, Amber S. Moody, Avery L. Wood, Paula A. Pimiento, James C. Elliott, Bhavya Sharma

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations

Abstract

Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexpensive instrumentation, minimal sample preparation, and rapid sample analysis. This review summarizes Raman spectroscopy-based techniques that have been used to advance the field of neuroscience in recent years.

Original languageEnglish
Pages (from-to)3461-3480
Number of pages20
JournalAnalyst
Volume145
Issue number10
DOIs
StatePublished - May 21 2020
Externally publishedYes

Funding

The authors thank the University of Tennessee for funding.

FundersFunder number
University of Tennessee

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