Raman and Infrared spectroscopies and X-ray diffraction data on bupivacaine and ropivacaine complexed with 2-hydroxypropyl−β−cyclodextrin

Murillo L. Martins, Juergen Eckert, Henrik Jacobsen, Everton C. dos Santos, Rosanna Ignazzi, Daniele Ribeiro de Araujo, Marie Claire Bellissent-Funel, Francesca Natali, Michael Marek Koza, Aleksander Matic, Eneida de Paula, Heloisa N. Bordallo

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16 Scopus citations

Abstract

The data presented in this article are related to the research article entitled “Probing the dynamics of complexed local anesthetics via neutron scattering spectroscopy and DFT calculations (http://dx.doi.org/10.1016/j.ijpharm.2017.03.051)” (Martins et al., 2017) [1]. This work shows the molecular and structural behavior of the local anesthetics (LAs) bupivacaine (BVC, C18H28N2O) and ropivacaine (RVC, C17H26N2O) before and after complexation with the water-soluble oligosaccharide 2-hydroxypropyl−β−cyclodextrin (HP-β-CD).

Original languageEnglish
Pages (from-to)25-29
Number of pages5
JournalData in Brief
Volume15
DOIs
StatePublished - Dec 2017
Externally publishedYes

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