@inproceedings{42710ef6fd584c6b89f71ed7bc822b9c,
title = "Purification of sperm from high WBC semen samples using a spiral channel",
abstract = "This study demonstrated the use of inertial microfluidic technology to separate sperm from white blood cells (WBC), the major contaminant of leukospermia semen samples, by flow focusing the sperm and WBCs. Fundamentals of inertial microfluidics were used to design the spiral channel. The fabricated spiral channel was verified in a series of experiments with WBC spiked semen samples. Concentration data and high speed streak images shows that sperm of high WBC semen sample can be significantly enriched by moderate sperm flow focusing and clear WBC flow focusing within a few minutes (∼5mins). These results suggest the promising potential for this technique to be used clinically.",
keywords = "Inertial microfluidics, Sperm, Spiral channel, White blood cells (WBC)",
author = "Jiyoung Son and Gale, {Bruce K.} and Hotaling, {James M.} and Carrell, {Douglas T.}",
year = "2016",
language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "248--249",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}