Prospects for atomic resolution and neutron crystallography in drug design

Leighton Coates; D. A.A. Myles

doi:10.2174/1389450043490613

Prospects for atomic resolution and neutron crystallography in drug design

Leighton Coates, D. A.A. Myles

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

The number of protein crystal structures being refined to atomic resolution is increasing each year as well as the size of proteins being studied. There are currently 346 structures in the protein data bank which have been refined to or beyond atomic resolution. The benefits of atomic resolution X-ray data are discussed along with a number of structrual example of biomedically relevant proteins. The complementary role of neutron diffraction will also be discussed.

Original language	English
Pages (from-to)	173-178
Number of pages	6
Journal	Current Drug Targets
Volume	5
Issue number	2
DOIs	https://doi.org/10.2174/1389450043490613
State	Published - Feb 2004
Externally published	Yes

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title = "Prospects for atomic resolution and neutron crystallography in drug design",

abstract = "The number of protein crystal structures being refined to atomic resolution is increasing each year as well as the size of proteins being studied. There are currently 346 structures in the protein data bank which have been refined to or beyond atomic resolution. The benefits of atomic resolution X-ray data are discussed along with a number of structrual example of biomedically relevant proteins. The complementary role of neutron diffraction will also be discussed.",

author = "Leighton Coates and Myles, {D. A.A.}",

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AB - The number of protein crystal structures being refined to atomic resolution is increasing each year as well as the size of proteins being studied. There are currently 346 structures in the protein data bank which have been refined to or beyond atomic resolution. The benefits of atomic resolution X-ray data are discussed along with a number of structrual example of biomedically relevant proteins. The complementary role of neutron diffraction will also be discussed.

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Prospects for atomic resolution and neutron crystallography in drug design

Abstract

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