Abstract
A method is described in which the interference of radiated secondharmonic electric fields generated by a pair of oriented molecules intercalated into double-stranded DNA is controlled and measured. The results show that the relative molecular orientation of the two molecules significantly changes the magnitude of the observed second-harmonic generation intensity, which is described by a simple model that accounts for the interferences of the radiated fields. The technique presented shows promise for future experiments investigating structural changes induced bythe formation of a DNA-biomolecule complex.
Original language | English |
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Pages (from-to) | 5756-5758 |
Number of pages | 3 |
Journal | Proceedings of the National Academy of Sciences of the United States of America |
Volume | 110 |
Issue number | 15 |
DOIs | |
State | Published - Apr 9 2013 |
Externally published | Yes |
Keywords
- Alignment
- Daunorubicin
- Equilibrium binding
- Nonlinear spectroscopy
- Phase