Preparation of magnetically separable N-halamine nanocomposites for the improved antibacterial application

Alideertu Dong, Shi Lan, Jinfeng Huang, Tao Wang, Tianyi Zhao, Weiwei Wang, Linghan Xiao, Xin Zheng, Fengqi Liu, Ge Gao, Yuxin Chen

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Magnetic N-halamine nanocomposites were synthesized through the encapsulation of the magnetic silica nanoparticles with antibacterial N-halamine polymer. The as-synthesized sample was characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier transform infrared (FTIR), X-ray diffraction (XRD), X-ray photoelectron spectra (XPS), and thermogravimetric analysis (TGA). The fabricated magnetic N-halamine nanocomposites possessed enhanced antibacterial activity against both Gram-positive and Gram-negative bacteria compared with their bulk counterparts. The effect of chlorine content of the magnetic N-halamine nanocomposites on the antibacterial activity was investigated. The magnetic N-halamine nanocomposites also exhibited super-paramagnetic behavior and had a saturation magnetization of 4.728emug -1 at room temperature, which made these nanocomposites separable magnetically after the antibacterial behavior. Performances derived from the synergism between magnetic core and antibacterial shell suggest that the magnetic N-halamine nanocomposites are qualified for antibacterial applications and separable by the aid of the external magnetic field.

Original languageEnglish
Pages (from-to)333-340
Number of pages8
JournalJournal of Colloid and Interface Science
Volume364
Issue number2
DOIs
StatePublished - Dec 15 2011
Externally publishedYes

Keywords

  • Antibacterial
  • Magnetic
  • N-halamine
  • Nanocomposites
  • Separation

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