Preliminary X-ray study of crystals of human C-reactive protein

L. J. DeLucas, T. J. Greenhough, S. A. Rule, D. A.A. Myles, Y. S. Babu, J. E. Volanakis, C. E. Bugg

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Abstract

Two different crystal forms of human C-reactive protein have been grown from solutions of 2-methyl-2,4-pentanediol. Both crystal forms are tetragonal, the space group for form I is P4122 (or P4322), and that for form II is P4222. The unit cell parameters for form I are a = b = 103.0(5) A ̊, c = 308.5(7) A ̊ and for form II are a = b = 103.1(2) A ̊, c = 312.7(6) A ̊. The crystals of form II diffract to at least 3.0 Å resolution, and are suitable for detailed structural studies.

Original languageEnglish
Pages (from-to)741-742
Number of pages2
JournalJournal of Molecular Biology
Volume196
Issue number3
DOIs
StatePublished - Aug 5 1987
Externally publishedYes

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