Porous Au-Ag nanospheres with high-density and highly accessible hotspots for SERS analysis

Kai Liu; Yaocai Bai; Lei Zhang; Zhongbo Yang; Qikui Fan; Haoquan Zheng; Yadong Yin; Chuanbo Gao

doi:10.1021/acs.nanolett.6b00868

Porous Au-Ag nanospheres with high-density and highly accessible hotspots for SERS analysis

Kai Liu, Yaocai Bai, Lei Zhang, Zhongbo Yang, Qikui Fan, Haoquan Zheng, Yadong Yin, Chuanbo Gao

Research output: Contribution to journal › Article › peer-review

408 Scopus citations

Abstract

Colloidal plasmonic metal nanoparticles have enabled surface-enhanced Raman scattering (SERS) for a variety of analytical applications. While great efforts have been made to create hotspots for amplifying Raman signals, it remains a great challenge to ensure their high density and accessibility for improved sensitivity of the analysis. Here we report a dealloying process for the fabrication of porous Au-Ag alloy nanoparticles containing abundant inherent hotspots, which were encased in ultrathin hollow silica shells so that the need of conventional organic capping ligands for stabilization is eliminated, producing colloidal plasmonic nanoparticles with clean surface and thus high accessibility of the hotspots. As a result, these novel nanostructures show excellent SERS activity with an enhancement factor of ∼1.3 × 10⁷ on a single particle basis (off-resonant condition), promising high applicability in many SERS-based analytical and biomedical applications.

Original language	English
Pages (from-to)	3675-3681
Number of pages	7
Journal	Nano Letters
Volume	16
Issue number	6
DOIs	https://doi.org/10.1021/acs.nanolett.6b00868
State	Published - Jun 8 2016
Externally published	Yes

Funding

C.G. acknowledges support from the National Natural Science Foundation of China (21301138), the startup fund, and operational fund for the Center for Materials Chemistry from Xi'an Jiaotong University. Y.Y. acknowledges support from the U.S. National Science Foundation (CHE-1308587). Z.Y. acknowledges support from Fundamental & Advanced Research Project of Chongqing, China (cstc2013jcyjC00001). The authors thank Professor Liqing Huang at School of Science, Xi'an Jiaotong University for help with FDTD simulations.

Funders	Funder number
U.S. National Science Foundation	CHE-1308587
Xi'an Jiaotong University
National Science Foundation	1308587
National Natural Science Foundation of China	21301138
Fundamental and Frontier Research Project of Chongqing	cstc2013jcyjC00001

Keywords

Porous nanoparticles
dealloying process
hotspots
plasmonic nanoparticles
surface-enhanced Raman scattering

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10.1021/acs.nanolett.6b00868

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title = "Porous Au-Ag nanospheres with high-density and highly accessible hotspots for SERS analysis",

abstract = "Colloidal plasmonic metal nanoparticles have enabled surface-enhanced Raman scattering (SERS) for a variety of analytical applications. While great efforts have been made to create hotspots for amplifying Raman signals, it remains a great challenge to ensure their high density and accessibility for improved sensitivity of the analysis. Here we report a dealloying process for the fabrication of porous Au-Ag alloy nanoparticles containing abundant inherent hotspots, which were encased in ultrathin hollow silica shells so that the need of conventional organic capping ligands for stabilization is eliminated, producing colloidal plasmonic nanoparticles with clean surface and thus high accessibility of the hotspots. As a result, these novel nanostructures show excellent SERS activity with an enhancement factor of ∼1.3 × 107 on a single particle basis (off-resonant condition), promising high applicability in many SERS-based analytical and biomedical applications.",

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author = "Kai Liu and Yaocai Bai and Lei Zhang and Zhongbo Yang and Qikui Fan and Haoquan Zheng and Yadong Yin and Chuanbo Gao",

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T1 - Porous Au-Ag nanospheres with high-density and highly accessible hotspots for SERS analysis

AU - Liu, Kai

AU - Bai, Yaocai

AU - Zhang, Lei

AU - Yang, Zhongbo

AU - Fan, Qikui

AU - Zheng, Haoquan

AU - Yin, Yadong

AU - Gao, Chuanbo

PY - 2016/6/8

Y1 - 2016/6/8

N2 - Colloidal plasmonic metal nanoparticles have enabled surface-enhanced Raman scattering (SERS) for a variety of analytical applications. While great efforts have been made to create hotspots for amplifying Raman signals, it remains a great challenge to ensure their high density and accessibility for improved sensitivity of the analysis. Here we report a dealloying process for the fabrication of porous Au-Ag alloy nanoparticles containing abundant inherent hotspots, which were encased in ultrathin hollow silica shells so that the need of conventional organic capping ligands for stabilization is eliminated, producing colloidal plasmonic nanoparticles with clean surface and thus high accessibility of the hotspots. As a result, these novel nanostructures show excellent SERS activity with an enhancement factor of ∼1.3 × 107 on a single particle basis (off-resonant condition), promising high applicability in many SERS-based analytical and biomedical applications.

AB - Colloidal plasmonic metal nanoparticles have enabled surface-enhanced Raman scattering (SERS) for a variety of analytical applications. While great efforts have been made to create hotspots for amplifying Raman signals, it remains a great challenge to ensure their high density and accessibility for improved sensitivity of the analysis. Here we report a dealloying process for the fabrication of porous Au-Ag alloy nanoparticles containing abundant inherent hotspots, which were encased in ultrathin hollow silica shells so that the need of conventional organic capping ligands for stabilization is eliminated, producing colloidal plasmonic nanoparticles with clean surface and thus high accessibility of the hotspots. As a result, these novel nanostructures show excellent SERS activity with an enhancement factor of ∼1.3 × 107 on a single particle basis (off-resonant condition), promising high applicability in many SERS-based analytical and biomedical applications.

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Porous Au-Ag nanospheres with high-density and highly accessible hotspots for SERS analysis

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Keywords

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