Piezoresistive cantilever array sensor for consolidated bioprocess monitoring

K. I.M. Seonghwan; Touhidur Rahman; Larry R. Senesac; Brian H. Davison; Thomas Thundat

doi:10.1002/sca.20159

Piezoresistive cantilever array sensor for consolidated bioprocess monitoring

K. I.M. Seonghwan, Touhidur Rahman, Larry R. Senesac, Brian H. Davison, Thomas Thundat

Biosciences Division

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Summary: Cellulolytic microbes occur in diverse natural niches and are being screened for industrial modification and utility. A microbe for consolidated bioprocessing (CBP) development can rapidly degrade pure cellulose and then ferment the resulting sugars into fuels. To identify and screen for novel microbes for CBP, we have developed a piezoresistive cantilever array sensor which is capable of simultaneous monitoring of glucose and ethanol concentration changes in a phosphate buffer solution. 4-mercaptophenylboronic acid and polyethyleneglycol-thiol are employed to functionalize each piezoresistive cantilever for glucose and ethanol sensing, respectively. Successful concentration measurements of glucose and ethanol with minimal interferences are obtained with our cantilever array sensor.

Original language	English
Pages (from-to)	204-210
Number of pages	7
Journal	Scanning
Volume	31
Issue number	5
DOIs	https://doi.org/10.1002/sca.20159
State	Published - Sep 2009

Keywords

4-mercaptophenylboronic acid
Ethanol
Glucose
Piezoresistive cantilever
Polyethyleneglycol- thiol

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10.1002/sca.20159

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title = "Piezoresistive cantilever array sensor for consolidated bioprocess monitoring",

abstract = "Summary: Cellulolytic microbes occur in diverse natural niches and are being screened for industrial modification and utility. A microbe for consolidated bioprocessing (CBP) development can rapidly degrade pure cellulose and then ferment the resulting sugars into fuels. To identify and screen for novel microbes for CBP, we have developed a piezoresistive cantilever array sensor which is capable of simultaneous monitoring of glucose and ethanol concentration changes in a phosphate buffer solution. 4-mercaptophenylboronic acid and polyethyleneglycol-thiol are employed to functionalize each piezoresistive cantilever for glucose and ethanol sensing, respectively. Successful concentration measurements of glucose and ethanol with minimal interferences are obtained with our cantilever array sensor.",

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T1 - Piezoresistive cantilever array sensor for consolidated bioprocess monitoring

AU - Seonghwan, K. I.M.

AU - Rahman, Touhidur

AU - Senesac, Larry R.

AU - Davison, Brian H.

AU - Thundat, Thomas

PY - 2009/9

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N2 - Summary: Cellulolytic microbes occur in diverse natural niches and are being screened for industrial modification and utility. A microbe for consolidated bioprocessing (CBP) development can rapidly degrade pure cellulose and then ferment the resulting sugars into fuels. To identify and screen for novel microbes for CBP, we have developed a piezoresistive cantilever array sensor which is capable of simultaneous monitoring of glucose and ethanol concentration changes in a phosphate buffer solution. 4-mercaptophenylboronic acid and polyethyleneglycol-thiol are employed to functionalize each piezoresistive cantilever for glucose and ethanol sensing, respectively. Successful concentration measurements of glucose and ethanol with minimal interferences are obtained with our cantilever array sensor.

AB - Summary: Cellulolytic microbes occur in diverse natural niches and are being screened for industrial modification and utility. A microbe for consolidated bioprocessing (CBP) development can rapidly degrade pure cellulose and then ferment the resulting sugars into fuels. To identify and screen for novel microbes for CBP, we have developed a piezoresistive cantilever array sensor which is capable of simultaneous monitoring of glucose and ethanol concentration changes in a phosphate buffer solution. 4-mercaptophenylboronic acid and polyethyleneglycol-thiol are employed to functionalize each piezoresistive cantilever for glucose and ethanol sensing, respectively. Successful concentration measurements of glucose and ethanol with minimal interferences are obtained with our cantilever array sensor.

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Piezoresistive cantilever array sensor for consolidated bioprocess monitoring

Abstract

Keywords

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