Abstract
Microcalorimetric optical and infrared spectroscopy is a method of determining the spectral absorption of small quantities of materials over a wide range of incident wavelengths. In this paper, the first spectroscopic results for microcantilevers coated with Bacillus anthracis (BA) are presented. These results, for B. anthracis from 2.5 to 14.5 μm, are compared with results from microcantilevers coated with Bacillus cereus (BC) and standard spectroscopic absorption data. The results demonstrate strong correlation between the deflection measurements and the reference spectroscopic absorption peaks. An advantage of this microcantilever-based method over traditional spectroscopy is that much smaller amounts of material (nanogram quantities) can be detected in comparison with the milligram amounts needed for standard methods. Another advantage is that the complete system can be relatively small without sacrificing spectral resolution.
| Original language | English |
|---|---|
| Pages (from-to) | 206-211 |
| Number of pages | 6 |
| Journal | Sensors and Actuators, B: Chemical |
| Volume | 114 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 30 2006 |
Funding
A non-infectious specimen of BA Ames spores was obtained from Bruce Harper of the U.S. Army Dugway Proving Ground, Utah. We also thank B.N. Khare of NASA Ames, CA, for preparing the BC spores. This work was supported with funds provided by the Department of Energy under the NN-22 program. Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6123 is managed by UT-Battelle, LLC for the Department of Energy under contract no. DE-AC05-0096OR22725.
Keywords
- Microcantilever
- Photothermal
- Sensor