ORNL_SAS: Software for calculation of small-angle scattering intensities of proteins and protein complexes

Elina Tjioe, William T. Heller

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

The program ORNL_SAS calculates solution small-angle X-ray and neutron scattering intensity profiles from a wide variety of structures, including atomic-resolution models of proteins and protein complexes, low-resolution models defined in any manner, or combinations of both. ORNL_SAS is capable of simultaneously generating multiple intensity profiles, such as a contrast-variation series, and evaluating the quality of the fit of the model profiles to experimental data in a single run of the program. The capabilities of the widely applicable approach make it possible to use ORNL_SAS as the intensity calculation engine of model-building applications for small-angle scattering data.

Original languageEnglish
Pages (from-to)782-785
Number of pages4
JournalJournal of Applied Crystallography
Volume40
Issue number4
DOIs
StatePublished - Jul 13 2007

Keywords

  • Contrast variation
  • Macromolecular crystallography
  • Small-angle scattering

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