Optimizing Transmit Field Inhomogeneity of Parallel RF Transmit Design in 7T MRI using Deep Learning

  • Zhengyi Lu
  • , Hao Liang
  • , Xiao Wang
  • , Xinqiang Yan
  • , Yuankai Huo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Ultrahigh field (UHF) Magnetic Resonance Imaging (MRI) provides a higher signal-to-noise ratio and, thereby, higher spatial resolution. However, UHF MRI introduces challenges such as transmit radiofrequency (RF) field (B1+) inhomogeneities, leading to uneven flip angles and image intensity anomalies. These issues can significantly degrade imaging quality and its medical applications. This study addresses B1+ field homogeneity through a novel deep learning-based strategy. Traditional methods like Magnitude Least Squares (MLS) optimization have been effective but are time-consuming and dependent on the patient's presence. Recent machine learning approaches, such as RF Shim Prediction by Iteratively Projected Ridge Regression and deep learning frameworks, have shown promise but face limitations like extensive training times and oversimplified architectures. We propose a two-step deep learning strategy. First, we obtain the desired reference RF shimming weights from multi-channel B1+ fields using random-initialized Adaptive Moment Estimation. Then, we employ Residual Networks (ResNets) to train a model that maps B1+ fields to target RF shimming outputs. Our approach does not rely on pre-calculated reference optimizations for the testing process and efficiently learns residual functions. Comparative studies with traditional MLS optimization demonstrate our method's advantages in terms of speed and accuracy. The proposed strategy achieves a faster and more efficient RF shimming design, significantly improving imaging quality at UHF. This advancement holds potential for broader applications in medical imaging and diagnostics.

Original languageEnglish
Title of host publicationMedical Imaging 2025
Subtitle of host publicationPhysics of Medical Imaging
EditorsJohn M. Sabol, Ke Li, Shiva Abbaszadeh
PublisherSPIE
ISBN (Electronic)9781510685888
DOIs
StatePublished - 2025
EventMedical Imaging 2025: Physics of Medical Imaging - San Diego, United States
Duration: Feb 17 2025Feb 21 2025

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume13405
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2025: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego
Period02/17/2502/21/25

Funding

This research was supported by NIH R01DK135597(Huo), DoD HT9425-23-1-0003(HCY), NIH NIDDK DK56942(ABF). This work was also supported by Vanderbilt Seed Success Grant, Vanderbilt Discovery Grant, and VISE Seed Grant. This project was supported by The Leona M. and Harry B. Helmsley Charitable Trust grant G-1903-03793 and G-2103-05128. This research was also supported by NIH grants R01EB033385, R01DK132338, REB017230, R01MH125931, and NSF 2040462. We extend gratitude to NVIDIA for their support by means of the NVIDIA hardware grant. This works was also supported by NSF NAIRR Pilot Award NAIRR240055. This manuscript has been co-authored by ORNL, operated by UT-Battelle, LLC under Contract No. DE-AC05-00OR22725 with the U.S.Department of Energy. This paper describes objective technical results and analysis. Any subjective views or opinions that might be expressed in the paper do not necessarily represent the views of the U.S. Department of Energy or the United States Government.

Keywords

  • RF shimming design
  • deep learning
  • magnetic field inhomogeneity

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