Optical pumping spin exchange3He gas cells for magnetic resonance imaging

W. Kim; S. S. Stepanyan; A. Kim; Y. Jung; S. Woo; M. Yurov; J. Jang

doi:10.1063/1.3215774

Optical pumping spin exchange³He gas cells for magnetic resonance imaging

W. Kim
, S. S. Stepanyan
, A. Kim
, Y. Jung
, S. Woo
, M. Yurov
, J. Jang

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

We present a device for spin-exchange optical pumping system to produce large quantities of polarized noble gases for Magnetic Resonance Imaging (MRI). A method and design of apparatus for pumping the polarization of noble gases is described. The method and apparatus enable production, storage and usage of hyperpolarized noble gases for different purposes, including Magnetic Resonance Imaging of human and animal subjects. Magnetic imaging agents breathed into lungs can be observed by the radio waves of the MRI scanner and report back physical and functional information about lung's health and desease. The technique known as spin exchange optical pumping is used. Nuclear magnetic resonance is implemented to measure the polarization of hyperpolarized gas. The cells prepared and sealed under high vacuum after handling Alkali metals into the cell and filling with the³He-N₂ mixture. The cells could be refilled. The³He reaches around 50% polarization in 5-15 hours.

Original language	English
Title of host publication	Spin Physics
Subtitle of host publication	18th International Spin Physics Symposium
Editors	Xiaochao Zheng, Yelena Prok, Matt Poelker, Donald G. Crabb, Simonetta Liuti, Donal B. Day
Publisher	American Institute of Physics Inc.
Pages	833-836
Number of pages	4
ISBN (Print)	9780735406865
DOIs	https://doi.org/10.1063/1.3215774
State	Published - Aug 4 2009
Externally published	Yes
Event	18th International Spin Physics Symposium 2008 - Charlottesville, United States Duration: Oct 6 2008 → Oct 11 2008

Publication series

Name	AIP Conference Proceedings
Volume	1149
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	18th International Spin Physics Symposium 2008
Country/Territory	United States
City	Charlottesville
Period	10/6/08 → 10/11/08

Funding

The authors had a lot of useful discussions with Prof. T. D. Averett at College of William and Merty. This work was supported by a grant from the Korea Research Foundation.

Keywords

He
MRI
Neutron
Optical pumping
Spin exchange
Spin filter

Access to Document

10.1063/1.3215774

Cite this

Kim, W., Stepanyan, S. S., Kim, A., Jung, Y., Woo, S., Yurov, M., & Jang, J. (2009). Optical pumping spin exchange³He gas cells for magnetic resonance imaging. In X. Zheng, Y. Prok, M. Poelker, D. G. Crabb, S. Liuti, & D. B. Day (Eds.), Spin Physics: 18th International Spin Physics Symposium (pp. 833-836). (AIP Conference Proceedings; Vol. 1149). American Institute of Physics Inc.. https://doi.org/10.1063/1.3215774

@inproceedings{cf1161b6650740c8a17bfd54861a433a,

title = "Optical pumping spin exchange3He gas cells for magnetic resonance imaging",

abstract = "We present a device for spin-exchange optical pumping system to produce large quantities of polarized noble gases for Magnetic Resonance Imaging (MRI). A method and design of apparatus for pumping the polarization of noble gases is described. The method and apparatus enable production, storage and usage of hyperpolarized noble gases for different purposes, including Magnetic Resonance Imaging of human and animal subjects. Magnetic imaging agents breathed into lungs can be observed by the radio waves of the MRI scanner and report back physical and functional information about lung's health and desease. The technique known as spin exchange optical pumping is used. Nuclear magnetic resonance is implemented to measure the polarization of hyperpolarized gas. The cells prepared and sealed under high vacuum after handling Alkali metals into the cell and filling with the3He-N2 mixture. The cells could be refilled. The3He reaches around 50\% polarization in 5-15 hours.",

keywords = "He, MRI, Neutron, Optical pumping, Spin exchange, Spin filter",

author = "W. Kim and Stepanyan, \{S. S.\} and A. Kim and Y. Jung and S. Woo and M. Yurov and J. Jang",

note = "Publisher Copyright: {\textcopyright} 2009 American Institute of Physics.; 18th International Spin Physics Symposium 2008 ; Conference date: 06-10-2008 Through 11-10-2008",

year = "2009",

month = aug,

day = "4",

doi = "10.1063/1.3215774",

language = "English",

isbn = "9780735406865",

series = "AIP Conference Proceedings",

publisher = "American Institute of Physics Inc.",

pages = "833--836",

editor = "Xiaochao Zheng and Yelena Prok and Matt Poelker and Crabb, \{Donald G.\} and Simonetta Liuti and Day, \{Donal B.\}",

booktitle = "Spin Physics",

}

Kim, W, Stepanyan, SS, Kim, A, Jung, Y, Woo, S, Yurov, M & Jang, J 2009, Optical pumping spin exchange³He gas cells for magnetic resonance imaging. in X Zheng, Y Prok, M Poelker, DG Crabb, S Liuti & DB Day (eds), Spin Physics: 18th International Spin Physics Symposium. AIP Conference Proceedings, vol. 1149, American Institute of Physics Inc., pp. 833-836, 18th International Spin Physics Symposium 2008, Charlottesville, United States, 10/6/08. https://doi.org/10.1063/1.3215774

Optical pumping spin exchange³He gas cells for magnetic resonance imaging. / Kim, W.; Stepanyan, S. S.; Kim, A. et al.
Spin Physics: 18th International Spin Physics Symposium. ed. / Xiaochao Zheng; Yelena Prok; Matt Poelker; Donald G. Crabb; Simonetta Liuti; Donal B. Day. American Institute of Physics Inc., 2009. p. 833-836 (AIP Conference Proceedings; Vol. 1149).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Optical pumping spin exchange3He gas cells for magnetic resonance imaging

AU - Kim, W.

AU - Stepanyan, S. S.

AU - Kim, A.

AU - Jung, Y.

AU - Woo, S.

AU - Yurov, M.

AU - Jang, J.

PY - 2009/8/4

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N2 - We present a device for spin-exchange optical pumping system to produce large quantities of polarized noble gases for Magnetic Resonance Imaging (MRI). A method and design of apparatus for pumping the polarization of noble gases is described. The method and apparatus enable production, storage and usage of hyperpolarized noble gases for different purposes, including Magnetic Resonance Imaging of human and animal subjects. Magnetic imaging agents breathed into lungs can be observed by the radio waves of the MRI scanner and report back physical and functional information about lung's health and desease. The technique known as spin exchange optical pumping is used. Nuclear magnetic resonance is implemented to measure the polarization of hyperpolarized gas. The cells prepared and sealed under high vacuum after handling Alkali metals into the cell and filling with the3He-N2 mixture. The cells could be refilled. The3He reaches around 50% polarization in 5-15 hours.

AB - We present a device for spin-exchange optical pumping system to produce large quantities of polarized noble gases for Magnetic Resonance Imaging (MRI). A method and design of apparatus for pumping the polarization of noble gases is described. The method and apparatus enable production, storage and usage of hyperpolarized noble gases for different purposes, including Magnetic Resonance Imaging of human and animal subjects. Magnetic imaging agents breathed into lungs can be observed by the radio waves of the MRI scanner and report back physical and functional information about lung's health and desease. The technique known as spin exchange optical pumping is used. Nuclear magnetic resonance is implemented to measure the polarization of hyperpolarized gas. The cells prepared and sealed under high vacuum after handling Alkali metals into the cell and filling with the3He-N2 mixture. The cells could be refilled. The3He reaches around 50% polarization in 5-15 hours.

KW - He

KW - MRI

KW - Neutron

KW - Optical pumping

KW - Spin exchange

KW - Spin filter

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U2 - 10.1063/1.3215774

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SN - 9780735406865

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EP - 836

BT - Spin Physics

A2 - Zheng, Xiaochao

A2 - Prok, Yelena

A2 - Poelker, Matt

A2 - Crabb, Donald G.

A2 - Liuti, Simonetta

A2 - Day, Donal B.

PB - American Institute of Physics Inc.

T2 - 18th International Spin Physics Symposium 2008

Y2 - 6 October 2008 through 11 October 2008

ER -