TY - JOUR
T1 - On scattered waves and lipid domains
T2 - Detecting membrane rafts with X-rays and neutrons
AU - Marquardt, Drew
AU - Heberle, Frederick A.
AU - Nickels, Jonathan D.
AU - Pabst, Georg
AU - Katsaras, John
N1 - Publisher Copyright:
© The Royal Society of Chemistry.
PY - 2015
Y1 - 2015
N2 - In order to understand the biological role of lipids in cell membranes, it is necessary to determine the mesoscopic structure of well-defined model membrane systems. Neutron and X-ray scattering are non-invasive, probe-free techniques that have been used extensively in such systems to probe length scales ranging from angstroms to microns, and dynamics occurring over picosecond to millisecond time scales. Recent developments in the area of phase separated lipid systems mimicking membrane rafts will be presented, and the underlying concepts of the different scattering techniques used to study them will be discussed in detail.
AB - In order to understand the biological role of lipids in cell membranes, it is necessary to determine the mesoscopic structure of well-defined model membrane systems. Neutron and X-ray scattering are non-invasive, probe-free techniques that have been used extensively in such systems to probe length scales ranging from angstroms to microns, and dynamics occurring over picosecond to millisecond time scales. Recent developments in the area of phase separated lipid systems mimicking membrane rafts will be presented, and the underlying concepts of the different scattering techniques used to study them will be discussed in detail.
UR - http://www.scopus.com/inward/record.url?scp=84948437695&partnerID=8YFLogxK
U2 - 10.1039/c5sm01807b
DO - 10.1039/c5sm01807b
M3 - Review article
C2 - 26428538
AN - SCOPUS:84948437695
SN - 1744-683X
VL - 11
SP - 9055
EP - 9072
JO - Soft Matter
JF - Soft Matter
IS - 47
ER -