Observation of biological samples using a scanning microwave microscope

Jewook Park, S. Hyun, A. Kim, T. Kim, K. Char

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

We present the application of a scanning microwave microscope technique to biological samples. Since dielectric properties of most biological samples originate mainly from the water they contain, we were able to obtain microscope images of biological samples by our scanning microwave microscope technique. As a model system, we have measured the electrical properties of water in the microwave region. The high dielectric constant and the large loss tangent of water were verified. Furthermore, we have measured the properties of water with differing amounts of sodium chloride concentration ranging from de-ionized water to the saturated solution. We have observed a significant change in the resonant frequency and Q value of the resonator as a function of sodium chloride concentration. The concentration dependence of the signals shows that our scanning microwave microscope technique can be useful for investigating the local electric behavior of biological samples with a simple model of ionic conduction.

Original languageEnglish
Pages (from-to)101-106
Number of pages6
JournalUltramicroscopy
Volume102
Issue number2
DOIs
StatePublished - Jan 2005
Externally publishedYes

Funding

This work is partially supported by the Korea Science and Engineering Foundation (KOSEF) through the Center for Strongly Correlated Materials Research (CSCMR).

FundersFunder number
Center for Strongly Correlated Materials Research
Korea Science and Engineering Foundation

    Keywords

    • 19, 24
    • Dielectric properties
    • Microscopic techniques in biophysics
    • Microwave technology
    • Scanning probe microscope

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