Numerical simulation and experimental study of resonance characteristics of QCM-P devices operating in liquid and their application in biological detection

Pengtao Wang; Junwei Su; Lin Gong; Mengyan Shen; Marina Ruths; Hongwei Sun

doi:10.1016/j.snb.2015.07.024

Numerical simulation and experimental study of resonance characteristics of QCM-P devices operating in liquid and their application in biological detection

Pengtao Wang
, Junwei Su
, Lin Gong
, Mengyan Shen
, Marina Ruths
, Hongwei Sun

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Quartz Crystal Microbalance - micropillar (QCM-P) devices rely on system resonance between the QCM crystal and micropillars directly fabricated on its surface to obtain ultrahigh sensitivity. A numerical model was developed to study the effect of hydrodynamic loadings on a QCM-P device. The effect of substrates with inherent resonant frequencies of 5 and 10 MHz on device performance was also studied numerically. The QCM-P device showed different resonant frequency and amplitude while operated in air or water. As a demonstration of applications of QCM-P in biological detection, a 5 MHz QCM-P device was used to measure acrylic acid grafted on oxygen plasma treated poly(methyl methacrylate) (PMMA) micropillar surfaces. The QCM-P device produced a much higher frequency response than a conventional QCM sensor.

Original language	English
Pages (from-to)	1320-1327
Number of pages	8
Journal	Sensors and Actuators, B: Chemical
Volume	220
DOIs	https://doi.org/10.1016/j.snb.2015.07.024
State	Published - Aug 3 2015
Externally published	Yes

Funding

This work was supported in part by the National Science Foundation under grants ECCS 0731125 and CMMI 0923403. The authors thank Dr. George Cernigliaro and Dr. Dai Wen from MicroChem Corp. (Newton, MA) for their help in fabricating PMMA micropillars.

Keywords

Improved mass sensitivity
Liquid phase
Micropillar
PMMA
QCM

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10.1016/j.snb.2015.07.024

Cite this

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title = "Numerical simulation and experimental study of resonance characteristics of QCM-P devices operating in liquid and their application in biological detection",

abstract = "Quartz Crystal Microbalance - micropillar (QCM-P) devices rely on system resonance between the QCM crystal and micropillars directly fabricated on its surface to obtain ultrahigh sensitivity. A numerical model was developed to study the effect of hydrodynamic loadings on a QCM-P device. The effect of substrates with inherent resonant frequencies of 5 and 10 MHz on device performance was also studied numerically. The QCM-P device showed different resonant frequency and amplitude while operated in air or water. As a demonstration of applications of QCM-P in biological detection, a 5 MHz QCM-P device was used to measure acrylic acid grafted on oxygen plasma treated poly(methyl methacrylate) (PMMA) micropillar surfaces. The QCM-P device produced a much higher frequency response than a conventional QCM sensor.",

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author = "Pengtao Wang and Junwei Su and Lin Gong and Mengyan Shen and Marina Ruths and Hongwei Sun",

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doi = "10.1016/j.snb.2015.07.024",

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T1 - Numerical simulation and experimental study of resonance characteristics of QCM-P devices operating in liquid and their application in biological detection

AU - Wang, Pengtao

AU - Su, Junwei

AU - Gong, Lin

AU - Shen, Mengyan

AU - Ruths, Marina

AU - Sun, Hongwei

PY - 2015/8/3

Y1 - 2015/8/3

N2 - Quartz Crystal Microbalance - micropillar (QCM-P) devices rely on system resonance between the QCM crystal and micropillars directly fabricated on its surface to obtain ultrahigh sensitivity. A numerical model was developed to study the effect of hydrodynamic loadings on a QCM-P device. The effect of substrates with inherent resonant frequencies of 5 and 10 MHz on device performance was also studied numerically. The QCM-P device showed different resonant frequency and amplitude while operated in air or water. As a demonstration of applications of QCM-P in biological detection, a 5 MHz QCM-P device was used to measure acrylic acid grafted on oxygen plasma treated poly(methyl methacrylate) (PMMA) micropillar surfaces. The QCM-P device produced a much higher frequency response than a conventional QCM sensor.

AB - Quartz Crystal Microbalance - micropillar (QCM-P) devices rely on system resonance between the QCM crystal and micropillars directly fabricated on its surface to obtain ultrahigh sensitivity. A numerical model was developed to study the effect of hydrodynamic loadings on a QCM-P device. The effect of substrates with inherent resonant frequencies of 5 and 10 MHz on device performance was also studied numerically. The QCM-P device showed different resonant frequency and amplitude while operated in air or water. As a demonstration of applications of QCM-P in biological detection, a 5 MHz QCM-P device was used to measure acrylic acid grafted on oxygen plasma treated poly(methyl methacrylate) (PMMA) micropillar surfaces. The QCM-P device produced a much higher frequency response than a conventional QCM sensor.

KW - Improved mass sensitivity

KW - Liquid phase

KW - Micropillar

KW - PMMA

KW - QCM

UR - https://www.scopus.com/pages/publications/84938336403

U2 - 10.1016/j.snb.2015.07.024

DO - 10.1016/j.snb.2015.07.024

M3 - Article

AN - SCOPUS:84938336403

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SP - 1320

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JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

ER -

Numerical simulation and experimental study of resonance characteristics of QCM-P devices operating in liquid and their application in biological detection

Abstract

Funding

Keywords

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