Noninvasive portal pressure estimation model using finite element analysis

P. Senthil Kumar, A. K. Thittai, R. Krishna Kumar

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Currently, portal pressure is measured by the standard method known as hepatic venous pressure gradient (HVPG). But it is an invasive procedure; therefore, an alternative noninvasive technique to estimate portal pressure is required to monitor portal hypertension. In this work, a 3D portal vein model is developed to study the acoustic interaction with microbubbles in the portal vein. Ultrasound scattering by ultrasound contrast agent (UCA) is modelled and analyzed using finite element analysis in order to estimate portal pressure. It was found from the analysis that the subharmonic component dropped by 1.5 dB as the portal pressure raised from 0 mmHg to 10 mmHg. Over the same pressure range, the fundamental component reduced by only 0.2 dB. The results suggest that the subharmonic component from the nonlinear response of microbubble is strongly affected by the ambient pressure, and the proposed model may be used to estimate portal pressure noninvasively.

Original languageEnglish
Title of host publicationBIODEVICES 2020 - 13th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 13th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2020
EditorsYe Xuesong, Ana Fred, Hugo Gamboa
PublisherSciTePress
Pages306-311
Number of pages6
ISBN (Electronic)9789897583988
StatePublished - 2020
Externally publishedYes
Event13th International Conference on Biomedical Electronics and Devices, BIODEVICES 2020 - Part of 13th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2020 - Valletta, Malta
Duration: Feb 24 2020Feb 26 2020

Publication series

NameBIODEVICES 2020 - 13th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 13th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2020

Conference

Conference13th International Conference on Biomedical Electronics and Devices, BIODEVICES 2020 - Part of 13th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2020
Country/TerritoryMalta
CityValletta
Period02/24/2002/26/20

Keywords

  • Finite Element Method
  • Microbubbles
  • Non-invasive
  • Portal Pressure
  • Subharmonic Scattering
  • Ultrasound

Fingerprint

Dive into the research topics of 'Noninvasive portal pressure estimation model using finite element analysis'. Together they form a unique fingerprint.

Cite this