Neutron stimulated emission computed tomography: Background corrections

Carey E. Floyd; Amy C. Sharma; Janelle E. Bender; Anuj J. Kapadia; Jessie Q. Xia; Brian P. Harrawood; Georgia D. Tourassi; Joseph Y. Lo; Matthew R. Kiser; Alexander S. Crowell; Ronald S. Pedroni; Robert A. Macri; Shigeyuki Tajima; Calvin R. Howell

doi:10.1016/j.nimb.2006.11.098

Neutron stimulated emission computed tomography: Background corrections

Carey E. Floyd, Amy C. Sharma, Janelle E. Bender, Anuj J. Kapadia, Jessie Q. Xia, Brian P. Harrawood, Georgia D. Tourassi, Joseph Y. Lo, Matthew R. Kiser, Alexander S. Crowell, Ronald S. Pedroni, Robert A. Macri, Shigeyuki Tajima, Calvin R. Howell

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Neutron stimulated emission computed tomography (NSECT) is an imaging technique that provides an in-vivo tomographic spectroscopic image of the distribution of elements in a body. To achieve this, a neutron beam illuminates the body. Nuclei in the body along the path of the beam are stimulated by inelastic scattering of the neutrons in the beam and emit characteristic gamma photons whose unique energy identifies the element. The emitted gammas are collected in a spectrometer and form a projection intensity for each spectral line at the projection orientation of the neutron beam. Rotating and translating either the body or the beam will allow a tomographic projection set to be acquired. Images are reconstructed to represent the spatial distribution of elements in the body. Critical to this process is the appropriate removal of background gamma events from the spectrum. Here we demonstrate the equivalence of two background correction techniques and discuss the appropriate application of each.

Original language	English
Pages (from-to)	329-336
Number of pages	8
Journal	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume	254
Issue number	2
DOIs	https://doi.org/10.1016/j.nimb.2006.11.098
State	Published - Jan 2007
Externally published	Yes

Funding

This work was supported in part by: NIH/NCI Grant 1-R21-CA106873-01 and NIH Training Grant 1-T32-EB001040.

Funders	Funder number
NIH/NCI	1-R21-CA106873-01
National Institutes of Health	1-T32-EB001040

Keywords

Background corrections
Biomedical imaging
Gamma-ray spectroscopy
Image quality
Neutrons

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10.1016/j.nimb.2006.11.098

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Floyd, C. E., Sharma, A. C., Bender, J. E., Kapadia, A. J., Xia, J. Q., Harrawood, B. P., Tourassi, G. D., Lo, J. Y., Kiser, M. R., Crowell, A. S., Pedroni, R. S., Macri, R. A., Tajima, S., & Howell, C. R. (2007). Neutron stimulated emission computed tomography: Background corrections. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 254(2), 329-336. https://doi.org/10.1016/j.nimb.2006.11.098

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title = "Neutron stimulated emission computed tomography: Background corrections",

abstract = "Neutron stimulated emission computed tomography (NSECT) is an imaging technique that provides an in-vivo tomographic spectroscopic image of the distribution of elements in a body. To achieve this, a neutron beam illuminates the body. Nuclei in the body along the path of the beam are stimulated by inelastic scattering of the neutrons in the beam and emit characteristic gamma photons whose unique energy identifies the element. The emitted gammas are collected in a spectrometer and form a projection intensity for each spectral line at the projection orientation of the neutron beam. Rotating and translating either the body or the beam will allow a tomographic projection set to be acquired. Images are reconstructed to represent the spatial distribution of elements in the body. Critical to this process is the appropriate removal of background gamma events from the spectrum. Here we demonstrate the equivalence of two background correction techniques and discuss the appropriate application of each.",

keywords = "Background corrections, Biomedical imaging, Gamma-ray spectroscopy, Image quality, Neutrons",

author = "Floyd, {Carey E.} and Sharma, {Amy C.} and Bender, {Janelle E.} and Kapadia, {Anuj J.} and Xia, {Jessie Q.} and Harrawood, {Brian P.} and Tourassi, {Georgia D.} and Lo, {Joseph Y.} and Kiser, {Matthew R.} and Crowell, {Alexander S.} and Pedroni, {Ronald S.} and Macri, {Robert A.} and Shigeyuki Tajima and Howell, {Calvin R.}",

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doi = "10.1016/j.nimb.2006.11.098",

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volume = "254",

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Floyd, CE, Sharma, AC, Bender, JE, Kapadia, AJ, Xia, JQ, Harrawood, BP, Tourassi, GD, Lo, JY, Kiser, MR, Crowell, AS, Pedroni, RS, Macri, RA, Tajima, S & Howell, CR 2007, 'Neutron stimulated emission computed tomography: Background corrections', Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, vol. 254, no. 2, pp. 329-336. https://doi.org/10.1016/j.nimb.2006.11.098

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AU - Sharma, Amy C.

AU - Bender, Janelle E.

AU - Kapadia, Anuj J.

AU - Xia, Jessie Q.

AU - Harrawood, Brian P.

AU - Tourassi, Georgia D.

AU - Lo, Joseph Y.

AU - Kiser, Matthew R.

AU - Crowell, Alexander S.

AU - Pedroni, Ronald S.

AU - Macri, Robert A.

AU - Tajima, Shigeyuki

AU - Howell, Calvin R.

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AB - Neutron stimulated emission computed tomography (NSECT) is an imaging technique that provides an in-vivo tomographic spectroscopic image of the distribution of elements in a body. To achieve this, a neutron beam illuminates the body. Nuclei in the body along the path of the beam are stimulated by inelastic scattering of the neutrons in the beam and emit characteristic gamma photons whose unique energy identifies the element. The emitted gammas are collected in a spectrometer and form a projection intensity for each spectral line at the projection orientation of the neutron beam. Rotating and translating either the body or the beam will allow a tomographic projection set to be acquired. Images are reconstructed to represent the spatial distribution of elements in the body. Critical to this process is the appropriate removal of background gamma events from the spectrum. Here we demonstrate the equivalence of two background correction techniques and discuss the appropriate application of each.

KW - Background corrections

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ER -

Neutron stimulated emission computed tomography: Background corrections

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