Abstract
A computer-assisted diagnostic (CAD) tool was developed for the diagnosis of acute pulmonary embolism (PE) in perfusion lung scans. Forty-five scans (with angiographic proof) were included in the study. The CAD tool was composed of two modules. The first module performs multifractal texture analysis on the posterior view of the perfusion scan. The second module is a decision algorithm that merges the multifractal parameters into a diagnosis regarding the presence or absence of PE. Linear and non-linear decision models were evaluated for the diagnostic task. A consensus neural network significantly outperformed all decision models including the physicians.
Original language | English |
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Pages (from-to) | 15-25 |
Number of pages | 11 |
Journal | Computers in Biology and Medicine |
Volume | 31 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2001 |
Externally published | Yes |
Funding
This work was supported by grant RG 98-0324 from the Whitaker Foundation and in part by grant R29-HL-52826 from the National Heart, Lung, and Blood Institute.
Funders | Funder number |
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National Heart, Lung, and Blood Institute | |
Whitaker Foundation | R29-HL-52826 |
Keywords
- Computer-aided diagnosis
- Fractal analysis
- Image processing
- Lung perfusion
- Neural networks
- Pulmonary embolism